sclerema


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Related to sclerema: Scleroderma, scleroderma neonatorum

sclerema

(sklərˈiːmə)
n
(Medicine) a condition in which body tissues harden, esp those of the fatty layer just under the skin
References in periodicals archive ?
Neonatal sclerema generally begins in the lower limbs and increases progressively, occurring in preterm neonates with an underlying disease and is associated with a grave prognosis, with an estimated mortality rate of 75%.
Other skin lesions found were petechiae (1), purpura (1), sclerema (1), loss of subcutaneous fat (1), hypospadiasis (1), generalized edema (1), ophthalmia neonatorum (1), micrognathia (2), lentigines (1), simian crease (2), umbilical hernia (1), prominent veins (1), hairy pinna (1), hydrocele (1), phimosis (1), insect bite (1), cleft lip and cleft palate (1) , cellulitis (1), scrotal dermatitis (1), triangular face (1).
Its clinical manifestation is very similar to the sclerema neonatorum whereas basic treatment method is about the same.
Sclerema neonatorum is a very rare panniculitis affecting primarily ill preterm neonates in the first week of life.
Skin: There may be multiple pustules, sclerema, mottling, umbilical redness and discharge.
Sclerema neonatorum is another rare condition characterized by diffuse hardening of the skin affecting infants up to 4 months of age with severe underlying disease and systemic symptoms.
Inclusion Criteria: Clinically suspected cases of neonatal sepsis with signs and symptoms suggestive of sepsis such as refusal to feed, feeding intolerance, lethargy, excess irritability, high pitched cry, seizures, temperature instability, apnea, respiratory distress, poor perfusion, tachypnea, bradycardia, abdominal distension, necrotizing enterocolitis, vomiting, sclerema were included.
Sclerema is defined as diffuse hardening of subcutaneous tissue, which usually spreads very rapidly to underlying structures; the skin in the involved areas cannot be picked up, and the subcutaneous tissue seems bound down to subjacent muscle and bone (1).
Miscellaneous Kasabach-Merritt phenomenon Purpura fulminans Kawasaki disease Sclerema neonatorum Erythromelalgia Other