None of the patients had erythromelalgia, sclerodermatous
changes, angioedema, bullous lesions, dermal mucinosis, nail changes, lichen planus, or pyoderma gangreosum.
Radiation-induced fibrosis (RIF), radiation recall dermatitis, post-irradiation sclerodermatous
panniculitis, and cancerous sclerosing recurrence are the main differential diagnoses.
changes are present, histology may reveal varying degree of collagen sclerosis resembling morphea.
Juvenile systemic sclerosis involves the skin, muscle, and visceral organs; therefore, the differential diagnosis should include other multiple-system organ diseases with skin involvement including juvenile dermatomyositis, mixed connective tissue disease, SLE, juvenile idiopathic arthritis, overlap syndrome, eosinophilic fasciitis, chronic graft versus host disease, nephrogenic systemic fibrosis, phenylketonuria with sclerodermatous
skin lesions, and syndromes of premature aging.
Twenty patients demonstrated an improvement of skin manifestations with six experiencing softening of sclerodermatous
changes and healing of skin ulcers in three.
Resolution of sclerodermatous
myocarditis after autologous stem cell transplantation.
it's a dynamic downhill process where we get more and more sclerodermatous
changes with time.
Patient had poliosis of eyelashes her legs and hands were very slender and spindle shaped with loss of subcutaneous fat, the skin was taut stretched tightly over the bone with sclerodermatous