This accumulation of drug response QTLs in one chromosomal region makes it tempting to speculate that the gene(s) associated with sedative-hypnotic drug
withdrawal may have effects on additional behavioral responses and would therefore be an even more important target for further investigations.
By examining Tennessee Medicaid files, they identified sedative-hypnotic drug
use among 16,262 drivers 65 to 84 years old.
are among the most commonly used medications in the United States.
About 45 percent of cases are linked to withdrawal from alcohol or sedative-hypnotic drugs
, or associated with the use of certain antidepressants, including tricyclic antidepressants such as imipramine, and selective serotonin reuptake inhibitor (SSRI) drugs such as fluoxetine, sertraline, or paroxetine.
Four: Insomnia, agitation, or delirium should not be initially treated with benzodiazepines or other sedative-hypnotic drugs
due to the increased risk of falls and fractures associated with these drugs.
In athletes with TBI, preliminary data suggest avoiding anticholinergics and other anxiolytics or sedative-hypnotic drugs
that may cause cognitive slowing, fatigue, or drowsiness.
The method of pentobarbital-induced sleep in mice is a classic pharmacological experiment for screening of sedative-hypnotic drugs
. The differential dose of pentobarbital can affect experimental results significantly.
The risks of the sedative-hypnotic drugs
include severe allergic reactions and complex sleep-related behaviors like sleep-driving.
In Canada, 13% of women versus 9% of men consume sedative-hypnotic drugs
. Data from the Canadian National Population Health Survey indicate that women are more likely to experience a major depressive episode, with annual incidence rates of depression twice as high as those of men.
The psychological and physiological effects of drugs are then explored in individual chapters covering alcohol; tobacco; narcotics; sedative-hypnotic drugs
; psychotherapeutic drugs; stimulants (cocaine, amphetamines, and caffeine); marijuana; and over-the-counter drugs.
Nonpharmacologic approaches are generally preferable in treating sleep disturbance among older adults because sedative-hypnotic drugs
are associated with an increased risk for falls, delirium, and functional decline in hospitalized elders (Foy et al., 1995).
Study I showed that a higher level of institutionalization was significantly (p < 0.05) associated with phase-advanced sleep/wake patterns, increased amounts of time spent in bed during the 24-hour period and increased usage of prescribed sedative-hypnotic drugs
. Poor sleep quality and disturbed sleep onset occurred significantly mostly in the.