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 (sĕm′ē-sĭn-thĕt′ĭk, sĕm′ī-)
1. Prepared by chemical synthesis from natural materials: a semisynthetic antibiotic.
2. Consisting of a mixture of natural and synthetic substances: a semisynthetic culture medium.


(Textiles) textiles partly synthetic and partly natural in composition


(ˌsɛm i sɪnˈθɛt ɪk, ˌsɛm aɪ-)

derived synthetically from one or more substances of natural origin.
sem`i•syn•thet′i•cal•ly, adv.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.semisynthetic - not of natural originsemisynthetic - not of natural origin; prepared or made artificially; "man-made fibers"; "synthetic leather"
chemical science, chemistry - the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions
artificial, unreal - contrived by art rather than nature; "artificial flowers"; "artificial flavoring"; "an artificial diamond"; "artificial fibers"; "artificial sweeteners"
References in periodicals archive ?
For lesions that are not fluctuant or purulent, appropriate first-line antibiotics are semisynthetic penicillins (dicloxacillin), first- or second-generation oral cephalosporins, macrolides, and clindamycin.
Cubicin (6 mg/kg IV once daily) was as effective as the standard of care: combination intravenous therapy with antistaphylococcal semisynthetic penicillin (2 g every 4 hours) or vancomycin (1 g every 12 hours), both with initial low-dose gentamicin.
The generic drug company's donations include packages of cephalosporin, semisynthetic penicillin, and cardiovascular, gastrointestinal and oral hypoglycemic agents.
Arbekacin, a semisynthetic aminoglycoside belonging to the kanamycin group, requires 2 modifications at the (6') aminogroup and the (2") hydroxyl group for inactivation, so this agent is not inactivated by known plasmid-mediated aminoglycoside-modifying enzymes.
He's improved that semisynthetic process tremendously," says Suffness.
Turning aluminum pistons is one use of a new semisynthetic metalworking fluid, developed for general and heavy-duty machining of both ferrous and nonferrous metals.
Structural modification toincrease activity of compounds will be carried out applying modern semisynthetic approaches in order to establish structureactivityrelationships.
Historically, CDC has programmatically characterized all opioid pain reliever deaths (natural and semisynthetic opioids, methadone, and other synthetic opioids) as "prescription" opioid overdoses (1).
The company added Oxacillin for Injection, USP is a semisynthetic penicillin indicated in the treatment of infections caused by penicillinase producing staphylococci which have demonstrated susceptibility to the drug.
Chlorophyllin, a mixture of semisynthetic, water-soluble derivatives of chlorophyll that is used as a food colorant and over-the-counter medicine, has been shown to be an effective inhibitor of aflatoxin hepatocarcinogenesis in animal models by blocking carcinogen bioavailability.