In the inner ear of vertebrates, the balance system consists of three semicircular canals that contain fluid and sensory hair
cells that detect movement of the head.
There's age-related hearing loss (starts at 60) or presbycusisin which hearing is affected by the loss of sensory hair
cells of the inner ear.
These melanocytes help maintain the high potassium levels of the fluid surrounding the sensory hair
cells in the ear.
Using its proprietary PCA platform, Frequency's lead product candidate stimulates the regrowth of sensory hair
cells in the inner ear to treat chronic noise induced hearing loss.
Tinnitus typically occurs from overexposure to loud noises that damage the sensory hair
cells in the inner ear.
Editor's Note : Co-author Josef Miller, PhD, who developed the formula, noted that lowering overstimulation-related oxidative stress has been shown to protect the ear's sensory hair
In white cats with inherited deafness, there is a loss of these sensory hair
cells, so sound waves cannot be converted into auditory signals that are perceived as sound.
As we get older, tiny sensory hair
cells in the inner ear die off or are damaged, a process that may be exacerbated by exposure to loud noise, poor cardiovascular health, and some medications, including aspirin and acetaminophen, as well as certain diuretics and antibiotics.
The squid statocyst and its sensory hair
cells share many characteristics with vertebrate vestibular systems yet maintain intriguing morphological differences, despite the functional commonalities of the two systems (Dilly et al.
One of the most common dizziness disorders, benign paroxysmal positional vertigo, or BPPV, occurs when calcium crystals in the utricle, one of the structures comprising the vestibular system, break loose and stimulate sensory hair
cells, causing mild to intense spinning sensations.
Beyond its findings connecting specific behaviours with genomic regions, the study also found that the same regions of the genome appear to control both the stickleback's ability to school as well as the anatomy of its lateral line, a system of organs that detect movement and vibration in water, and contain the same sensory hair
cells found in the human ear.
Previous attempts to "grow" inner-ear hair cells in standard cell culture systems have worked poorly in part because necessary cues to develop hair bundles-a hallmark of sensory hair
cells and a structure critically important for detecting auditory or vestibular signals-are lacking in the flat cell-culture dish.