serum sickness

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serum sickness

n.
A hypersensitive reaction to the administration of a foreign serum, characterized by fever, swelling, skin rash, and enlargement of the lymph nodes.

serum sickness

n
(Pathology) an allergic reaction, such as vomiting, skin rash, etc, that sometimes follows 2-3 weeks after an injection of a foreign serum
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Noun1.serum sickness - a delayed allergic reaction to the injection of an antiserum caused by an antibody reaction to an antigen in the donor serum
allergic reaction, allergy - hypersensitivity reaction to a particular allergen; symptoms can vary greatly in intensity
References in periodicals archive ?
We report 2 cases of HLA-B27-associated Meniere disease, and we describe their clinical and immunocytologic features as determined by the patients' serum reactions with mouse inner ears.
The goal of our investigation was twofold: (1) to illustrate a possible association between carriage of the HLA-B27 allele and the presentation of autoimmune inner ear disease or autoimmune Meniere disease symptomatology in 2 patients and (2) to investigate the immunocytologic features of this association--namely the presence of a circulating autoantibody reaction as demonstrated by the patients' serum reactions with mouse inner ear tissue substrates.

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