sialic acid

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Related to sialic acid: salicylic acid

si·al·ic acid

Any of a group of amino carbohydrates that are components of mucoproteins and glycoproteins, especially in animal tissue and blood cells.

[Greek sialon, saliva + -ic.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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A negative correlation was previously observed between sialic acid levels of LDL and the capacity of these lipoprotein particles to cause intracellular accumulation of cholesterol [24].
Mothers with healthy babies had breast milk full of carbohydrates that contained a chemical called sialic acid, the team reports in the Feb.
Lung collagen hydroxyproline, uronic acid, hexosamine, serum sialic acid, [gamma]-glutamyl transpeptidase, vascular endothelial growth factor (VEGF), granulocyte monocyte colony-stimulating factor and other cytokine levels were significantly lowered in the treated group of animals.
The levels of protein-bound sialic acid (PBSA), high-sensitivity C-reactive protein (hsCRP), malondialdehyde (MDA), protein carbonyl (PCO), vitamin B12, and folic acid in maternal serum were measured.
The GlcNAc residues can be extended with additional monosaccharide linkages involving galactose, fucose, or sialic acid residues.
Varki, "Mechanism of uptake and incorporation of the non-human sialic acid N-glycolylneuraminic acid into human cells," Journal of Biological Chemistry, vol.
Hemagglutinin binds to sialic acid, a sugar moiety on the surface of many cells.
Tamiflu and another anti-influenza drug, Relenza, focus on interrupting neuraminidase's ability to help influenza detach from an infected cell's surface by digesting sialic acid, a sugar on the surface of the cell.
Nevertheless, these studies have been restricted to gangliosides containing the N-acetylated variant of sialic acid (NeuAc) [24, 25].
To account for any cell-culture induced mutations, sialic acid (SA) binding affinities of both MDCK cell- and embryonated hens' egg-grown stocks of Ca/CO-1, Ca/WY, Ca/CO-2, and Eq/CO were determined using a solid-phase binding assay [31, 32], with slight modification of the original protocol to equilibrate the viruses assayed to ~20,000 matrix gene copies [33, 34].