sickle cell


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Related to sickle cell: sickle cell trait, Sickle cell crisis

sickle cell

n.
An abnormal, crescent-shaped red blood cell that results from a single change in the amino acid sequence of the cell's hemoglobin, which causes the cell to contort, especially under low-oxygen conditions.

sick′le cell`



n.
an elongated, often sickle-shaped red blood cell, caused by defective hemoglobin.
[1925–30]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sickle cell - an abnormal red blood cell that has a crescent shape and an abnormal form of hemoglobin
erythrocyte, RBC, red blood cell - a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus
References in periodicals archive ?
US-based therapeutics developer Emmaus Life Sciences's marketing authorization application for Xyndari has been fully validated and is now under assessment by the European Medicines Agency (EMA) for the treatment of sickle cell disease, the company said.
The Tuskegee experiment is fresh in a lot of people's minds even though that was decades ago," says Andemariam, who is also chief medical officer for the Sickle Cell Disease Association of America.
This disease affects so many across the nation, and I hope our efforts will help to bring Sickle Cell awareness to the forefront of medical research so that we will continue to see more developments in the near future.
The cardiac effects of sickle cell anaemia on the left ventricle have been extensively investigated in adults.
Bahrain Sickle Cell Anaemia Patient Care Society chairman Zakreya Al Kadhem said it was difficult to persuade patients not to fast because of their strong religious beliefs.
Data from the firm's Phase three sickle cell disease trial indicated a decrease in the frequency of sickle cell crises and hospitalisations, and a reduction in cumulative days hospitalised, and a lower incidence of the life-threatening acute chest syndrome.
To address the challenges, the American Society of Hematology in September launched the Sickle Cell Disease Coalition, of which APHA is a member, and released "State of Sickle Cell Disease: 2016 Report" to evaluate four priority areas: access to care, training and professional education, research and clinical trials, and global health.
CDC is also working with partners to develop the Sickle Cell Data Collection Program (http://www.
Like sickle cell, it gets worse with age, requires strict daily drug regimens, and often results in hospitalization.
About 8 to 10 percent of African-Americans have sickle cell trait.
As free radical promotes increased and irreversible sickling of RBC membrane by damaging it, oxidative stress was assessed in sickle cell disease patients of western Odisha by measuring serum MDA as a by-product of lipid peroxidation, with simultaneous measurement of levels of antioxidant vitamins (vitamin E and vitamin C) as a possible beneficial therapeutic supplements in prevention of sickle cell complications.
All TLOD chapters have programs that benefit sickle cell disease research and families throughout the United States.