sildenafil

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sil·den·a·fil

(sĭl-dĕn′ə-fĭl)

A drug, C₂₂H₃₀N₆O₄S, used to treat sexual dysfunction by increasing the level of cyclic GMP, which increases blood flow to erectile tissues.

[Perhaps alteration of s(ulfon)yl + (pyrimi)dine + ph(en)yl.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

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Noun

sildenafil - virility drug (trade name Viagra) used to treat erectile dysfunction in men

sildenafil citrate, Viagra

anti-impotence drug, virility drug - drug to treat impotence attributable to erectile dysfunction

Translations

sildenafil

n sildenafil m, sildenafilo (INN)

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References in periodicals archive ?

Sildenafil is a phosphodiesterase 5 and 6 (PDE-5, PDE-6) inhibitors that induce vasodilation.

Changes in Retinal and Choroidal Vascular Blood Flow after Oral Sildenafil: An Optical Coherence Tomography Angiography Study

Sildenafil is an antagonist of phosphodiesterase type 5 (PDE-5), which inhibits cGMP catabolism, stimulating the activation of mechanisms that involve cGMP.

Treatment with Sildenafil and Donepezil Improves Angiogenesis in Experimentally Induced Critical Limb Ischemia

that Gln-817 is critical for cGMP, sildenafil, and vardenafil affinity.

Sildenafil Can Affect Innate and Adaptive Immune System in Both Experimental Animals and Patients

Phosphodiesterase type 5 inhibitors (PDE5) are a group of drugs (sildenafil, tadalafil, vardanafil) that are widely used as a standard treatment for erectile dysfunction (ED) and some of them for pulmonary hypertension as well (sildenafil and tadalafil).

Efficiency of sildanefil monotherapy in benign prostatic hyperplasia/Nova opcija medikamentoznog tretmana benigne hiperplazije prostate i simptoma donjeg urinarnog trakta

She said: "The drug names eligible for reimbursement in 2018 were Sildenafil, Tadalafil and Vardenafil."

[euro]1.4M SPLURGED ON VIAGRA-STYLE DRUGS; Sinn Fein TD calls for similar budget to supply contraceptives for women

Pfizer announced that a Phase 3 study to assess the efficacy and safety of intravenous sildenafil when added to inhaled nitric oxide for the treatment of newborns with Persistent Pulmonary Hypertension did not meet its primary efficacy endpoint.

Pfizer says Phase 3 trial of revatio did not meet primary efficacy endpoint

[USA], Apr 6 (ANI): A new research conducted in rats has found that treating preeclampsia with sildenafil citrate (Viagra) may help protect the cardiovascular health of the offspring.

Treating preeclampsia with sildenafil may protect offspring's cardiovascular health: Study

Brooklyn, NY, March 22, 2019 --(PR.com)-- USALESS Issues Voluntary Nationwide Recall of LEOPARD Miracle Honey Due to Presence of Undeclared Sildenafil

USALESS Issues Voluntary Nationwide Recall of LEOPARD Miracle Honey

LAS VEGAS -- Increased rates of persistent pulmonary hypertension (PPH) in neonates put the brakes on STRIDER, an international placebo-controlled study looking at sildenafil as a treatment for early-onset intrauterine growth restriction (IUGR).

Sildenafil associated with PPH in neonates with IUGR

In a laboratory analysis, the FDA found that "E-Cialis HelloCig E-Liquid" contained both sildenafil and tadalafil, and that "E-Rimonabant HelloCig E-Liquid" contained sildenafil.

Alert issued over e-liquids with undeclared drugs

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