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A drug, C22H30N6O4S, used to treat sexual dysfunction by increasing the level of cyclic GMP, which increases blood flow to erectile tissues.

[Perhaps alteration of s(ulfon)yl + (pyrimi)dine + ph(en)yl.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sildenafil - virility drug (trade name Viagra) used to treat erectile dysfunction in men
anti-impotence drug, virility drug - drug to treat impotence attributable to erectile dysfunction
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n sildenafil m, sildenafilo (INN)
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Sildenafil is a phosphodiesterase 5 and 6 (PDE-5, PDE-6) inhibitors that induce vasodilation.
Sildenafil is an antagonist of phosphodiesterase type 5 (PDE-5), which inhibits cGMP catabolism, stimulating the activation of mechanisms that involve cGMP.
that Gln-817 is critical for cGMP, sildenafil, and vardenafil affinity.
Phosphodiesterase type 5 inhibitors (PDE5) are a group of drugs (sildenafil, tadalafil, vardanafil) that are widely used as a standard treatment for erectile dysfunction (ED) and some of them for pulmonary hypertension as well (sildenafil and tadalafil).
She said: "The drug names eligible for reimbursement in 2018 were Sildenafil, Tadalafil and Vardenafil."
Pfizer announced that a Phase 3 study to assess the efficacy and safety of intravenous sildenafil when added to inhaled nitric oxide for the treatment of newborns with Persistent Pulmonary Hypertension did not meet its primary efficacy endpoint.
[USA], Apr 6 (ANI): A new research conducted in rats has found that treating preeclampsia with sildenafil citrate (Viagra) may help protect the cardiovascular health of the offspring.
Brooklyn, NY, March 22, 2019 --( USALESS Issues Voluntary Nationwide Recall of LEOPARD Miracle Honey Due to Presence of Undeclared Sildenafil
LAS VEGAS -- Increased rates of persistent pulmonary hypertension (PPH) in neonates put the brakes on STRIDER, an international placebo-controlled study looking at sildenafil as a treatment for early-onset intrauterine growth restriction (IUGR).
In a laboratory analysis, the FDA found that "E-Cialis HelloCig E-Liquid" contained both sildenafil and tadalafil, and that "E-Rimonabant HelloCig E-Liquid" contained sildenafil.