simeprevir


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Related to simeprevir: daclatasvir, sofosbuvir, telaprevir
Translations

simeprevir

n simeprevir m
References in periodicals archive ?
The tender number includes the following medicines: Tender no: 1, Atc code: J05ap05, Generic name: Simeprevir, Dispensing form: Capsules, Strength: 150 mg, Packing: 28 pcs.
Simeprevir (Olysio[R]) is part of the combination antiviral treatment for patients with HCV genotype 1 infection.
Telaprevir, Boceprevir, Simeprevir, Faldaprevir, and Asunaprevir drugs improved the SVR rate against different HCV genotypes but could not eliminate the use of interferon completely [12-15].
M2 PHARMA-December 11, 2017-Medivir reports on termination of simeprevir license by Janssen
M2 EQUITYBITES-December 11, 2017-Medivir reports on termination of simeprevir license by Janssen
Nine medicines incorporated received more than 250 responses (just one had more than 500): fingolimod for the 3rd line of treatment of multiple sclerosis (530 responses); cinacalcet and paricalcitol for therapy related to secondary hyperparathyroidism on chronic renal diseases requiring dialysis; antiviral dolutegravir sodium for HIV-related infections; palivizumab for the prevention of infections related to the respiratory syncytial virus, and sofosbuvir, daclatasvir and simeprevir indicated for chronic hepatitis C.
the GG or TG variant) were treated with pegylated interferon alpha-2a (PEG IFN), ribavirin, and simeprevir and were randomly assigned to receive or not to receive (control group) 2,000 IU per day of vitamin D.
They found that annual treatment rates more than doubled from 2,726 to 6,679 patients when pegylated interferon was introduced, declined for a while and then rose modestly to 4,900 patients when boceprevir and telaprevir were introduced, declined again to an all-time low of 2,609 and then rebounded to 9,180 patients when sofosbuvir and simeprevir were introduced, and finally skyrocketed to 31,028 patients when ledipasvir/ sofosbuvir and paritaprevir/ritonavir/ombitasvir/dasabuvir were introduced.
Medivir AB (STO:MVIRB), a research based pharmaceutical company with a focus on oncology, announced on Thursday that it has reached an agreement with Janssen to outlicense the commercial rights to the Nordics for simeprevir and future simeprevir containing products.
These agents include simeprevir, sofosbuvir, ledipasvir, and the combination of ombitasvir-paritaprevir-ritonavir plus dasabuvir (brand name, Viekira Pak).
However, clinical guidelines from the American Association for the Study of Liver Diseases (4) (AASLD) recommend testing for Q80K in genotype 1a prior to using simeprevir in interferon-containing regimens, and more recently in cirrhotic patients that are going to start sofosbuvir (SOF) and simeprevir (SIM).
Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: The COSMOS randomised study.