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A statin drug, C25H38O5, that blocks the body's synthesis of cholesterol and is used to lower cholesterol (especially LDL) levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.

[sim- (perhaps alteration of syn-, pref. indicating attachment on the same side of the plane as a double bond; see syn-) + -vastatin, statin suffix; see pravastatin.]
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Noun1.simvastatin - an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks
lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase


n simvastatina
References in periodicals archive ?
SAN DIEGO -- The presentation of the landmark IMPROVE-IT study at last November's American Heart Association scientific sessions told only half the story of the clinical impact of lipid-lowering with the combination of ezetimibe and simvastatin as opposed to simvastatin alone.
The patients were given 60 grams of simvastatin (Zocor[R]) or placebo; this treatment was started on the same day as antibiotic therapy and was given until discharge from the ICU, through death, or after the 28th day.
Washington, March 19 ( ANI ): Researchers have suggested that simvastatin, a cheap cholesterol lowering drug, might be a potential treatment option for the secondary progressive, or chronic, stage of multiple sclerosis (MS), which is currently untreatable.
In order to improve the mechanical properties and bioactivity of the nanofibers, bioactive glass nanoparticles were added while simvastatin drug (aiming to speed up the growth of the bone tissue) was loaded in the fibers to increase the efficiency of the scaffold.
This effect was also observed with atorvastatin and simvastatin.
The Journal of the American College of Cardiology published the finding of Danish researchers of reductions in glucose tolerance and coenzyme Q10 levels in men treated with simvastatin, one of several statin drugs commonly prescribed to lower cholesterol.
Simvastatin-Teva tablets, containing simvastatin, are prescription medicine indicated for hypercholesterolaemia.
Comparisons to simvastatin in patients with dyslipidemia at high risk of coronary heart disease showed the two statins to be equivalent.
Earlier work showed simvastatin improves blood flow in the brains of year-old lab mice with Alzheimer's.
Results showed that a significantly greater percentage of patients achieved this goal with CRESTOR[TM] (rosuvastatin) than with equal or double doses of atorvastatin (Lipitor[R]) or simvastatin.
On May 12, 2004, the United Kingdom allowed the BTC purchase of low dose (10 mg) simvastatin (Nash and Nash 2004) for patients at moderate risk for coronary heart disease, for whom prescription strength statins were not indicated.
Simvastatin treatment of an adolescent with hyperimmunoglobulinemia D and periodic fever syndrome unresponsive to anti-inflammatory strategies has resulted in a favorable outcome.