5g/l), deficiency of Growth Hormone due to defective hepatic, biosynthesis of somatomedin
, insulin like growth factor-1 (IGF-1) and sex steroid deficiency play main their role.
Effect of ethanol on serum concentrations of somatomedin
C and the growth hormone (GH) secretion stimulated by the releasing hormone (GHRH).
His early study on the measurement of IGF-I (then called somatomedin
C) showed that successful therapy of acromegaly was associated with normalization of values, but measurements were made weeks to months after treatment (21).
The division of endocrinology reported that growth hormone treatment could be initiated in the patient whose somatomedin
C and insulin like growth factor binding protein 3 levels were found to be low.
They added that several factors related to the person's state of nutrition or stress are known to stimulate secretion: starvation, hypoglycemia exercise, excitement and trauma, also it has been found that growth hormone causes the liver and other tissues as muscles to form several small proteins called somatomedins
, many of the somatomedin
effect on growth are similar to the effects of insulin on growth, they are called insulin like growth factor.
The effect of hypothyroidism on growth, serum growth hormone, the growth hormone-dependent somatomedin
, insulin-like growth factor, and its carrier protein in rats.
IGF-I, also called somatomedin
C, is a small polypeptide hormone with an approximate molecular weight of 7kDa .
Deficiency of serotonin, tryptophan, norepinephrine, dopamine, histidine, methionine, and somatomedin
Its other names include IGF-1 (insulinlike growth factor type 1), somatomedin
, and sulfation factor.
IGF-1 is also called somatomedin
C, a small 70-amino acid polypeptide with a molecular weight of 7649 kDa (5).
Effect of zinc supplementation on growth hormone secretion, IGF-I, IGFBP-3, somatomedin
generation, alkaline phosphatase, osteocalcin and growth in prepubertal children with idiopathic short stature.
Other pituitary hormones including somatomedin
(c-IGF1), growth factor and prolactin were within normal limits.