The nervous excitement of which we speak pursued Valentine even in her sleep, or rather in that state of
somnolence which succeeded her waking hours; it was then, in the silence of night, in the dim light shed from the alabaster lamp on the chimney-piece, that she saw the shadows pass and repass which hover over the bed of sickness, and fan the fever with their trembling wings.
The gnawing of profound discomfort existed side by side with an incredible disposition to
somnolence, as though he had been buffeted and worried into drowsiness.
This
somnolence did I disturb when I taught that NO ONE YET KNOWETH what is good and bad:--unless it be the creating one!
Thus, they could not understand his excessive
somnolence in the forenoon, nor his excessive activity at night.
Then there is least
somnolence in us; and for an hour, at least, some part of us awakes which slumbers all the rest of the day and night.
In early July 2019, the Company completed enrollment in the Phase 1b proof-of-concept trial with AM-201 in antipsychotic-induced weight gain and
somnolence. The trial is being conducted at a single trial site in Europe and enrolled 50 healthy volunteers who received either AM-201 or placebo concomitantly with olanzapine over four weeks.
The most common adverse events (AEs) in the trial were
somnolence, headache, diarrhea, and sedation.
According to the agency, the most common side effects reported in the clinical trials for Lyrica in adults are dizziness,
somnolence, dry mouth, swelling, blurred vision, weight gain and abnormal thinking (primarily difficulty with concentration/attention).
The most commonly reported side effects of pregabalin include dizziness,
somnolence, dry mouth, swelling, blurred vision, weight gain, and difficulty concentrating or paying attention.
'He upholds the worldwide honor he alone gave our country-not by talking or posturing or worse sleeping on the job with eyes open so the public won't note the
somnolence but by slugging it out, putting his face in the line of repeated punches.
Somnolence, disequilibrium, and gastrointestinal disturbance were the most common adverse effects, occurring in 13%, 7%, and 7% of patients, respectively.
In this study, lemborexant had rates of discontinuation due to adverse events (AEs) comparable to placebo, with the most common AEs in the lemborexant arms being headache and
somnolence.
