sphingomyelin


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Related to sphingomyelin: cerebroside, sphingolipid

sphingomyelin

(ˌsfɪŋɡəʊˈmaɪəlɪn)
n
(Biochemistry) biochem any of a group of phospholipids, derived from sphingosine, that occur in biological membranes, being especially abundant in the brain
[from sphingo-, from Greek sphingein to bind + myelin]
References in periodicals archive ?
22) found that this abundance of sphingomyelin diminished in parallel with a progressive increase in HDL density.
Value of Amniotic Fluid Sphingomyelin Quantification in Fetuses with G1-a Gene Mutations of Unclear Significance
Cer is an intermediate in synthesis of glycosphingolipid, sphingomyelin, sphingosine, and Cer-1-P, compounds that are increasingly recognized as mediators of cellular processes.
Binding of influenza A virus to monosialoganglioside (GM3) reconstituted in glucosylceramide and sphingomyelin membranes.
Molecular species of GC, LC, Cer, and CTH were identified by precursor ion scanning for mass-to-charge ratio (m/z) 264, and molecular species of sphingomyelin (SM) and PC were identified by precursor ion scanning for m/z 184 in positive-ion mode.
For example, the use of an unnatural spectrophotometric substrate for assaying ASM has recently been shown to be problematic in that a mutant form of this enzyme shows normal activity on the artificial substrate but low activity on the naturally occurring sphingomyelin substrate (29).
Choline is the precursor for the neurotransmitter acetylcholine, and phosphatidylcholine and sphingomyelin (components of cell membranes).
Cooperation between the NS5B and p7 increase the Virion infectivity with the decrease in sphingomyelin level in Virion [17].
The phosphate group may join to a variety of alcohols to produce the following very critical constituents of animal cell membranes which include phosphatidyl inositol, phosphatidyl serine, phosphatidyl choline, phosphatidyl ethanolamine, and sphingomyelin.
It is possible that its chemical composition of sphingomyelin, phosphorylcholine, and ceramides somehow prevents carotenes from being deposited, or the minute amounts present are grossly imperceptible.
Sphingomyelin is the most abundant of the 7 types of sphingolipids, constituting approximately 5-6 mol % of total lipids.
Caveolae, which is a special lipid raft structure formed from cell membrane invagination, was enriched in cholesterol and sphingomyelin, and primarily played the important role in membrane transport, signal transduction, substrate transport and endocytosis (Martin, 2013).