spironolactone


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spi·ro·no·lac·tone

 (spī′rə-nō-lăk′tōn, spī-rō′-, spī-rŏn′ə-)
n.
An aldosterone antagonist and antiandrogen, C24H32O4S, that promotes diuresis and is used to treat fluid retention, androgenic syndromes in women, and hypertension.

[Alteration of spirolactone : Latin spīra, coil; see spiral + lactone.]

spironolactone

(ˌspaɪrənəʊˈlæktəʊn)
n
(Pharmacology) a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure
[C20: from spiro-2 + linking syllable -no- + lactone]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.spironolactone - a synthetic corticosteroid (trade name Aldactone) used to treat hypertensionspironolactone - a synthetic corticosteroid (trade name Aldactone) used to treat hypertension
antihypertensive, antihypertensive drug - a drug that reduces high blood pressure
adrenal cortical steroid, corticoid, corticosteroid - a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response; "adrenal cortical steroids are used to treat many different conditions"
Translations

spironolactone

n espironolactona
References in periodicals archive ?
Limited Tenders are invited for Supply of Tab Hydrochlor thiazide 25mg Tab Spironolactone 25 mg
The number of courses of spironolactone prescribed for acne per 100 female patients treated by dermatologists increased by 291% during the study period, from 2.
Spironolactone use "remains relatively uncommon" compared with oral antibiotics, the researchers pointed out, noting that the 2013 data show that, for every course of spironolactone, there were 2.
The approval marks the first and only FDA-approved oral liquid dosage form of the potassium-sparing diuretic spironolactone.
Patients were categorized according to possible etiology into four groups; (1) chronic renal failure (CRF), (2) acute renal failure (ARF), and (3) angiotensin-converting-enzyme inhibito /angiotensin receptor bloker (ACEI/ARB) use, and (4) spironolactone use.
M2 EQUITYBITES-August 8, 2017-CMP Pharma awarded US FDA approval for Spironolactone Oral Suspension in 25 mg/5 ml
M2 PHARMA-August 8, 2017-CMP Pharma awarded US FDA approval for Spironolactone Oral Suspension in 25 mg/5 ml
I have been using Beyaz and Yaz for several years in my PCOS patients for the lower androgenic activity of the drospirenone based on the same assumption and its similarity to spironolactone.
WAILEA, HAWAII--While spironolactone is an old drug, it remains a safe and effective treatment option for management of acne in women, according to Julie Harper, MD, of the University of Alabama at Birmingham, speaking at the SDEF Hawaii Dermatology Seminar.
When a triple regimen of an ACE inhibitor or ARB, calcium channel blocker, and a thiazide diuretic fails to achieve the target blood pressure, try adding spironolactone.
The interaction between galectin-3, [beta]-blockers, renin-angiotensin system (RAS) blockade, and spironolactone on outcome was evaluated in TIME-CHF and validated in GISSI-HF.
25 mg daily PO, Spironolactone @ 1mg/kg twice daily and Enalapril @ 0.