spironolactone


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spi·ro·no·lac·tone

 (spī′rə-nō-lăk′tōn, spī-rō′-, spī-rŏn′ə-)
n.
An aldosterone antagonist and antiandrogen, C24H32O4S, that promotes diuresis and is used to treat fluid retention, androgenic syndromes in women, and hypertension.

[Alteration of spirolactone : Latin spīra, coil; see spiral + lactone.]

spironolactone

(ˌspaɪrənəʊˈlæktəʊn)
n
(Pharmacology) a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure
[C20: from spiro-2 + linking syllable -no- + lactone]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.spironolactone - a synthetic corticosteroid (trade name Aldactone) used to treat hypertensionspironolactone - a synthetic corticosteroid (trade name Aldactone) used to treat hypertension
antihypertensive, antihypertensive drug - a drug that reduces high blood pressure
adrenal cortical steroid, corticoid, corticosteroid - a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response; "adrenal cortical steroids are used to treat many different conditions"
Translations

spironolactone

n espironolactona
References in periodicals archive ?
You can do this screening test in a patient on any medication except spironolactone.
Spironolactone as a class is a potassium-sparing diuretic.
Bayer's novel mineralocorticoid antagonist, finerenone has the potential to capitalize on this unmet need as it is predicted to have renal sparing effects compared to spironolactone (Pfizer's Aldactone, generics) and eplerenone (Pfizer's Inspra, generics).
Spironolactone, usually used for high blood pressure and heart failure, could help people suffering from osteoarthritis.
They believe that drug called spironolactone offers a cheap and safe way to ease patients' suffering without any dangerous side-effects, the Daily Express reported.
This can be in the form of hormonal treatment (estrogen and progesterone), and other non-hormonal tablets like metformin and spironolactone which can be very beneficial to ameliorate symptoms if used in combination.
5 mg once daily and a combination of torsemide 20 mg and spironolactone 50 mg was initiated.
Her medication was including prednisone 5 mg/d, cyclophosphamide 2x50 mg/d, ramipril 1x5 mg/d, aspirin 100 mg/day, spironolactone 1x25 mg/d and furosemide 1x40 mg/d.
Medication All children in the CHD group were on diuretic medication for heart failure; 4 patients were also on salicylic acid, 4 were on potassium citrate, and 4 on spironolactone, in combination (Table 1).
In this paper in the British Medical Journal the authors report on a study that investigates whether exposure to spironolactone treatment affects the risk of incident breast cancer in women over 55 years of age.
03 mg of ethinyl estradiol with 3 mg of drospirenone) was the first COC that contained drospirenone, a spironolactone analogue, that was approved, followed by Yaz (0.
The patient had a history of diabetes mellitus and liver cirrhosis with ascites; he had been taking a potassium-holding diuretic, spironolactone, for 8 months.