This syndrome was first discovered by Sutton and Lawton in 1973 (2), and it accounts for only 2% of all splanchnic
CARDIOVASCULAR ABNORMALITIES develop in patients with advanced chronic liver disease to produce a hyperdynamic systemic circulation with splanchnic
vasodilation, decreased systemic vascular resistance, and increased cardiac output (J Hepatol.
Another series of studies have shown that through actions in rostral ventrolateral medulla (rVLM), stimulation of both gallbladder and gastric afferent activates splanchnic
nerves and increases blood pressure.
However due to the creation of pneumoperitoneum, increase in intraabdominal pressure causes liver splanchnic
vessels to undergo mesenteric hypoxia, ischemia-reperfusion injury and associated increase in oxidative stress .
In addition to hepatic parenchymal disease evaluation on grey scale imaging, the introduction of duplex doppler ultrasonography has proven to be a break-through in evaluation of splanchnic
hemodynamic changes set in secondary to portal hypertension, a known insidious complication of chronic liver disease10,15, 16
The basic abnormality is a vascular aberration in which the splanchnic
venous return drains directly into the systemic veins (IVC or the left renal, left iliac or left hepatic vein), diverting the mesenteric circulation away from the liver.
In addition, a significant portion of the amino acids absorbed from the meal will be retained in the splanchnic
area, mainly the gut."
Depending on the extent of PP, visceral perfusion, splanchnic
perfusion, portal venous flow, and renal blood flow may also decrease (2-4).
Although we did not observe vascular stenosis or thrombosis on contrast-enhanced CT, the patient's prior right lobectomy might have resulted in hemodynamic change from altered splanchnic
Differences in splanchnic
metabolism between late gestation and early lactation dairy cows.
It is innervated by preganglionic fibres of the splanchnic
Increased portal inflow resistance and splanchnic
(related to internal organs) hyperdynamic circulation are the primary factors in the pathophysiology of PH, explained Ying-Ying Yang, MD, PhD, MPH, of the Division of Gastroenterology and Hepatology, Department of Medicine of the National Yang-Ming University School of Medicine, Taiwan.