The present study was designed to determine the frequency of HPV in newly diagnosed patients of oesophageal squamous cell carcinoma
. The rationale of this study was that no local study has been conducted to determine the frequency of HPV in OSCC which has a huge geographical variation.
Histologic Tumor Grade.--Based on the WHO classification, 3 histologic grades of conventional squamous cell carcinoma
are used: well, moderately, and poorly differentiated.
Basal cell carcinoma (BCC) and squamous cell carcinoma
(SCC)are the most common skin cancers and are lumped into Non Melanoma Skin Cancers (NMSC)4.
New Delhi [India], Jan 8 ( ANI ): Actor-producer Rakesh Roshan has been diagnosed with early stage squamous cell carcinoma
. The news was broken by his son Hrithik Roshan on social media.
Oral cancer represents 5-10% of all human malignancies and 94% of all oral malignancies is squamous cell carcinoma
(OSCC) .1,2 It is one of the top ten most frequent cancers present around the globe with an incidence of 10-15/100,000 with male to female ratio of 2.5:1.
Squamous cell carcinoma
of thyroid with lymph nodal and pulmonary metastases
Moderately differentiated squamous cell carcinoma
and well-differentiated squamous cell carcinoma
were proportionally high in males when compared to females, but there was no statistical significant difference.
Microscopically, all cases were diagnosed as squamous cell carcinoma
characterized by islands of neoplastic epithelial cells with keratinized layers (cell nests) in the centre and well developed fibrous connective tissue stroma in adjacent areas (Fig.
Current biomarkers for lung cancer include carcinoma embryonic antigen (CEA), sialyl Lewis X antigen (SLX), squamous cell carcinoma
(SCC) antigen, and cytokeratin fragment (CYFRA) 21-1, but these are not sensitive enough to detect tumors early, another professor Ryo Nagashio said in the study appears in The American Journal of Pathology.
Marketing authorisation application for the product is based on a Phase two pivotal, single-arm, open-label clinical trial of cemiplimab for advanced CSCC (EMPOWER-CSCC 1) in addition to Phase one data from two advanced cutaneous squamous cell carcinoma
Carcinomatous infiltration of squamous cell carcinoma
was observed in the excisional biopsy of the lesion.
As stated in Introduction, among head and neck cancers, reported cases of concomitant squamous cell carcinoma
and EPM are extremely rare, and this represents the first report of synchronous EPM and hypopharyngeal carcinoma.