start codon


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to start codon: stop codon

start codon

n.
A codon, AUG in eukaryotes and either GUG or UUG in bacteria, that signals the initiation of translation and the first amino acid in a polypeptide chain. Also called chain initiation codon.
Translations
codon d’initiation
Mentioned in ?
References in periodicals archive ?
Start and end codons were annotated using the bivalve mitochondrial codon table and BlastP was used to confirm the position of the start codon and the length of the protein sequences.
In this phenomenon, Met 62 or Met 116 acts as a second start codon. When a premature termination codon arises in the upstream sequence, the downstream sequence of Met62 or Met116 can escape nonsense-mediated mRNA decay and translate into protein with residual function [Figure 1]c, resulting in blockade of the metabolism of AdoCbl in mitochondria.
The reference sequence was according to Genbank accession number Z26653, with the A of the ATG start codon on position 1.
Lee and Kwon presented consecutive DE multiple bit embedding (CDE-MBE) [17] and least-squares-based prediction error expansion (LS-PE) [18] of neighbor code values of noncoding DNA sequences while preventing a false start codon. They reported that LS-PE has 0.36 bits per nucleotide base (bpn) more than CDE-MBE [18].
The objective of this study was to use two molecular marker systems, start codon targeted (SCoT) and inter-simple sequence repeat (ISSR), to assess the genetic relationship and diversity of 75 sugarcane parental clones from Chinese sugarcane breeding program.
The trigger RNA finds the complementary single-stranded toehold sequence and opens up the ribosome binding site (RBS) [3] and start codon within its hairpin structure.
At this stage, an initiator methionyl-tRNA (met-tRNAi) is in the ribosomal peptidyl (P) site at the mRNA start codon [1,13].
Sequencing analysis of the ompk35 and ompk36 genes revealed the presence of the insertion sequence IS1 between the promoter region and the start codon of the ompK35 gene, and the presence of the IS908 disrupting the ompK36 gene.
There are 64 codons; 61 correspond to the 20 amino acids of which 1 (AUG) is a start codon. The remaining 3 codons (UAA UAG and UGA) are stop codons.
Tusavims has a potential upstream start codon MSS in a weaker Kozak consensus sequence than MAQ (Figure, panel A), which we selected as the start codon.
Ribosomes complete the process by translation of mRNA molecules into the proteins of interest, from the start codon (generally AUG) to the stop codon (generally UAA).