statin


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stat·in

 (stăt′n)
n.
Any of a class of lipid-lowering drugs that reduce serum cholesterol levels by inhibiting a key enzyme involved in the biosynthesis of cholesterol.

[From the names of such lipid-lowering drugs as pravastatin.]

statin

(ˈstætɪn)
n
(Pharmacology) any of a class of drugs, including atorvastatin and simvastatin, that lower the levels of low-density lipoproteins in the blood by inhibiting the activity of an enzyme involved in the production of cholesterol in the liver
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.statin - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase
atorvastatin, Lipitor - an oral drug (trade name Lipitor) that is effective in lowering triglycerides; potent in reducing LDL cholesterol because higher doses can be given
Baycol, cerivastatin - an oral drug (trade name Baycol) to reduce blood cholesterol levels
fluvastatin, Lescol - least expensive statin drug (trade name Lescol); usually taken orally at bedtime
lovastatin, Mevacor - an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
Pravachol, pravastatin - an oral drug (trade name Pravachol) administered to reduce blood cholesterol levels; recommended after nonfatal heart attacks
simvastatin, Zocor - an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks
Translations

statin

n estatina
References in periodicals archive ?
For every 1,000 at risk of heart problems, if those people take a statin for three years, the drugs will prevent seven non-fatal heart attacks, four strokes and two deaths.
Statin use in cirrhosis patients lowers the risk of death, Dr.
Research findings have been inconsistent, however, with some studies showing a lower risk, some showing no difference and some showing a higher risk of Parkinson's disease in statin users.
The team, from the National Cancer Centre in Beijing, found that a common type of statin called lipophilic statin showed a particularly strong protective effective in breast cancer patients, compared with hydrophilic statins, which had a much weaker effect.
Information on statin use was obtained from medical records and a self-reporting questionnaire.
For appropriate patients, statin drugs reduce cardiovascular death and disability rates.
NEW ORLEANS--High-intensity statin therapy in patients with peripheral artery disease was associated with significant reductions in amputations as well as mortality during up to 5 years of follow-up in the first large study to examine the relationship, Shipra Arya, MD, reported at the American Heart Association scientific sessions.
The study, however, did not take into account statin use before the patients went on Medicare.
These signs and symptoms were reported to be mild and transient, usually disappearing after discontinuation of the statin.
Cholesterol-lowering statin drugs, which are supposed to reduce the risk of heart disease, actually contribute to heart failure and atherosclerosis, according to a 2015 Japanese pharmacological review.