These patients usually have other skin findings including palmoplantar keratoderma, white plaques on the mouth, and skin cysts (steatocystoma
multiplex and vellus hair cysts).
An association between HS and several other inflammatory and genetic disorders have also been reported in the literature, including acne conglobata, spondyloarthropathies, pyoderma gangrenosum, synovitis-acne-pustulosis-hyperostosis-osteitis syndrome, Dowling-Degos disease, fox den disease, florid steatocystoma
multiplex, pyoderma vegetans, and pityriasis rubra pilaris (6-14).
multiplex is an uncommon inherited condition in which multiple lesions are formed, most commonly appearing on the trunk, axillae, and groin.
Women with steatocystoma
multiplex, an autosomal inherited disease, have multiple sebaceous cysts in the axillae and femoral fold as well .
multiplex (SM) and eruptive vellus hair cysts (EVHC) are uncommon benign tumors of the pilosebaceous unit.
On clinical bases, a differential diagnose of pilomatricoma and steatocystoma
multiplex were kept.
observed that pilomatricoma was the most common benign tumor followed by dermoid cyst followed by steatocystoma
multiplex, syringoma, and trichilemmal cyst.
Findings of histopathological examination were compatible with steatocystoma
[Figure 1], so she was diagnosed with steatocystoma
The clinical differential diagnosis for vulvar syringoma is broad and should exclude such diseases as epidermal cyst, steatocystoma
multiplex, lymphangioma circumstriptum, chronic lichen simplex, angiokeratoma in Fox-Fordyce disease, senile angioma, condyloma acuminatum, candidiasis, scabies, pediculosis, allergic and irritant contact dermatitis, psoriasis and lichen sclerosus et atrophicus (2, 7, 8, 19-21).
Based on simple clinical observation, a diagnosis of Steatocystoma
multiplex was made, the patient refused skin biopsy.
No cases (0%) of chondroid syringoma, steatocystoma
, sebaceous hyperplasia, and sebaceous adenoma were found.
Previously, these lesions have been attributed to sebaceous cysts, calcified steatocystoma
, fibroma, atheroma and xanthoma.[sup.8,9] More recently, it has been suggested that they are the result of dartos muscle necrosis and degeneration with resulting dystrophic calcification of the dartos muscle in a process similar to the calcification of uterine leiomyoma.[sup.10]