In the first study, conducted at the Stelic
Institute in Japan, STAM NASH mice were administered CRV431 orally, once daily for three weeks at a dose of 20 mg/kg, which decreased the extent of fibrosis by 57% compared to vehicle control.
The Stelic Institute & Co, Tokyo, Japan, announced it has developed a new treatment method for acute liver failure.
Research results show that for the first time that hepatic cells possess a mechanism for attempting to repair the wide-ranging hepatic cell necrosis associate with drug-induced acute liver failure, and that anti-CXCL10 antibodies strengthen this type of self-repairing function at the in vivo level, Stelic says.
Tokyo, Japan, Oct 27, 2006 - (JCN Newswire) - Stelic Institute & Co., a Tokyo-based bioventure company specializing in regenerative medicine, has announced development of a new treatment method for acute liver failure.
"Hepatic cell replication has great potential as an alternative to current methods of treating liver damage, such as transplants and cellular therapy," said Stelic chairman Hiroyuki Yoneyama.
Stelic's Stem Cell Dynamism Research Team has shown that hepatic cord regeneration in acute liver cell damage is regulated at the in vivo level by a protein called chemokine CXCL10.
[USPRwire, Wed Aug 14 2013] Global Markets Direct's pharmaceuticals report, "Stelic Institute & Co.
This report is built using data and information sourced from Global Markets Direct's proprietary databases, Stelic Institute & Co.'s corporate website, SEC filings, investor presentations and featured press releases, both from Stelic Institute & Co.
* Review of current pipeline of Stelic Institute & Co.
Tokyo, Japan, Oct 13, 2006 - (JCN Newswire) - Stelic Institute & Co., a Tokyo-based bioventure company specializing in regenerative medicine, has carried out groundbreaking research on the dynamics of somatic stem cells in vivo, filing nine patent applications related to stem cell research and other areas since the Company's establishment in November 2004.
Stelic's business model is both novel and unique, with medical researchers engaged in consideration of new treatments for disorders from the very earliest stages of drug development.
At Stelic, physicians - qualified medical researchers who have worked with patients and understood their needs - are at the center of research and development.