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Related to steric: Steric hindrance, Steric effect


 (stĕr′ĭk, stîr′-) also ster·i·cal (-ĭ-kəl)
Of or relating to the spatial arrangement of atoms in a molecule.

ster′i·cal·ly adv.


(ˈstɛrɪk; ˈstɪər-) or


(Chemistry) chem of, concerned with, or caused by the spatial arrangement of atoms in a molecule
[C19: from stereo- + -ic]
ˈsterically adv


(ˈstɛr ɪk, ˈstɪər-)

of or pertaining to the spatial relationships of atoms in a molecule.
[1895–1900; ster (eo)- + -ic]
References in periodicals archive ?
A pharmacophore, for example, as defined by the International Union of Pure and Applied Chemistry, is "an ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target and to trigger (or to block) its biological response.
This carrier function is important because molecules such as 6PPD migrate very slowly due to the steric constraints.
In CONCERT we will develop a method based on the use of nuclear magnetic resonance spectroscopy in solution that will provide very detailed descriptions of such changes by using the information about structural heterogeneity contained in a parameter that is exquisitely sensitive to molecular shape called residual dipolar coupling measured in steric alignment.
In the small intestine, the macromolecules cannot permeate through tight junctions of the intestinal cell wall because of multiple factors, including molecular size and steric hindrance effects, and are vulnerable to further enzymatic and hydrolytic degradation.
The trends with the alcohols follow the trends of the isocyanates where the lower steric hindrance of reactive moieties leads to larger heats of reaction.
The team also clarified aspects of the second major theory of olfaction, termed the "shape theory of olfaction", which suggests that steric aspects of odorants are central in the so-called "hand-in-glove" or "lock and key" interaction of odors with odorant receptors.
By using suitable polymeric steric stabilizer can prevent from the precipitation of conducting polymer particles [27].
A major breakthrough was the discovery of self-doped polyaniline; however, the material shows reduced mechanical stability and decreased conductivity due to steric effects.
antibodies) very unlikely because of steric hindrance that occurs following binding of a hapten to one binding protein.
High-performance dispersants also typically employ ethylene oxide chains to provide nonionic steric stabilization characteristics.
Phe80 and Phe141 have been suggested to function as a steric gate conferring substrate specificity for the enzyme (Petrotchenko et al.
It was used to calculate electrostatic, steric and hydrophobic descriptors for the given set of molecules and to perform regression to build a model by selecting a set of descriptors that describe the activity of the molecule.