cells secrete insulin-like growth factor-I and II (IGF-I, II), which stimulate the growth of epithelial tumor cells via the EGFR signal transduction cascade.
Like most breast tumours including breast cancers, fibroadenomas consist of a mixed population of different cell types, called epithelial cells and stromal
tumors (GISTs), though the most common mesenchymal tumors of the GI tract, are rare accounting approximately 1% to 3% of all gastrointestinal tumors.
BONN, Germany, February 1, 2018 -- Multipotent stromal
cells have long been a hot topic in medical research.
Objective: Gastrointestinal stromal
tumors (GISTs) are rare mesenchymal tumors of the gastrointestinal tract, which frequently cause intraabdominal metastases.
This descriptive study was carried out at Pathology Department, Shifa International Hospital from 2007 to 2016; all sex cord stromal
tumours diagnosed during this time period were included.
hyperplasia (PASH) is a benign proliferative lesion of the breast stroma characterized by slit-like pseudovascular spaces lined by endothelial-like spindle cells.
A distinct fibroepithelial neoplasm characterised by leaf-like arrangement of spindle shaped stromal
cell with elongated epithelial component in breast was first named as Cystosarcoma Phyllodes by Johannes Muller in 1838.
Background: Extra-gastrointestinal stromal
tumor is defined as a mesenchymal neoplasm arising from soft tissues outside the gastrointestinal tract.
tumors (GIST) are the most common mesenchymal tumors of the digestive tract and are generally asymptomatic.
IL-33 production by stromal
cells in lymph nodes (LN) and spleen is crucial for efficient viral clearance, however, the precise cellular source and signals involved in secretion of this nuclear alarmin during viral infection are unknown.
The classification of PT proposed by the World Health Organization (WHO) into benign, borderline, and malignant is based on a combination of several histologic features, including stromal
cellularity, nuclear atypia, mitotic activity, stromal
overgrowth, and tumor margin appearance.