subacute sclerosing panencephalitis

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subacute scle·ros·ing panencephalitis

An often fatal degenerative disease of the central nervous system occurring chiefly in young people, caused by slow infection with a measles virus and characterized by progressive loss of mental and motor functions ending in dementia and paralysis.

[sclerosing, from sclerose, to harden, back-formation from sclerosed.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

sub′acute scle•ros′ing pan′en•ceph•a•li′tis

(sklɪˈroʊ sɪŋ ˈpæn ɛnˌsɛf əˈlaɪ tɪs, ˌpæn-)
an infection of the central nervous system caused by the measles virus, occurring in children and adolescents several years after a measles attack and characterized by progressive personality changes, seizures, and muscular incoordination.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.subacute sclerosing panencephalitis - a rare chronic progressive encephalitis caused by the measles virus and occurring primarily in children and young adults; death usually occurs within three years; characterized by primary measles infection before the age of two years
panencephalitis - diffuse inflammation of the entire brain
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References in periodicals archive ?
On the basis of her investigations and clinical co-relation the diagnosis of subacute sclerosing panencephalitis (SSPE) was made.
Satoh et al., "Neurodegenerative mechanisms in subacute sclerosing panencephalitis," Journal of Child Neurology, vol.
Adult onset subacute sclerosing panencephalitis: clinical profile of 39 patients from a tertiary care centre.
HIV-associated neuro-cognitive disorder EBV: primary CNS lym-phoma JC virus: PML [not equal to] Prions: spongiform ence- phalopathy Spinal Acute viral HIV-1 vacuolar cord myelitis myelopathy ADEM * HTLV-1 myelopathy * Acute disseminated encephalomyelitis [dagger] Subacute sclerosing panencephalitis [not equal to] Progressive multifocal leucoencephalopathy.
It has been shown that MV induces mitochondrial structural abnormalities in dendrites during persistent infection of the brain termed subacute sclerosing panencephalitis (SSPE)28 and also has been associated with apoptosis.
Susanne Prendergast got measles when she was just two - but it was eight years before she started to show signs of the rare measles-relatebrain disorder Subacute Sclerosing Panencephalitis in the summer of 1982.
Some sufferers have even been known to develop a progressive and fatal brain infection known as subacute sclerosing panencephalitis, which may not develop until years after the bout of measles.
Subacute sclerosing panencephalitis with atypical onset: Clinical, computed tomographic, and magnetic resonance imaging correlations.
Jack's disease - subacute sclerosing panencephalitis - is slowly killing him.
As mentioned, measles virus is known to cause persistent infections in the brain that can lead to subacute sclerosing panencephalitis and "measles virus inclusion body encephalitis." [41] A correlation between Paget's disease and measles virus infection is controversial.
INTRODUCTION: Subacute sclerosing panencephalitis (SSPE) is a slow progressive degeneration of the central nervous system caused by a persistent defective measles virus infection.

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