subacute sclerosing panencephalitis

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subacute scle·ros·ing panencephalitis

(sklə-rō′sĭng)

An often fatal degenerative disease of the central nervous system occurring chiefly in young people, caused by slow infection with a measles virus and characterized by progressive loss of mental and motor functions ending in dementia and paralysis.

[sclerosing, from sclerose, to harden, back-formation from sclerosed.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

sub′acute scle•ros′ing pan′en•ceph•a•li′tis

(sklɪˈroʊ sɪŋ ˈpæn ɛnˌsɛf əˈlaɪ tɪs, ˌpæn-)
n.

an infection of the central nervous system caused by the measles virus, occurring in children and adolescents several years after a measles attack and characterized by progressive personality changes, seizures, and muscular incoordination.

[1950]

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Noun

subacute sclerosing panencephalitis - a rare chronic progressive encephalitis caused by the measles virus and occurring primarily in children and young adults; death usually occurs within three years; characterized by primary measles infection before the age of two years

Bosin's disease, Dawson's encephalitis, inclusion body encephalitis, sclerosing leukoencephalitis, SSPE, subacute inclusion body encephalitis, subacute sclerosing leukoencephalitis, Van Bogaert encephalitis

panencephalitis - diffuse inflammation of the entire brain

Translations

SSPE

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References in periodicals archive ?

On the basis of her investigations and clinical co-relation the diagnosis of subacute sclerosing panencephalitis (SSPE) was made.

Subacute sclerosing panencephalitis: a rare neurological disorder in pregnancy

Satoh et al., "Neurodegenerative mechanisms in subacute sclerosing panencephalitis," Journal of Child Neurology, vol.

Changes in cerebrospinal fluid biomarkers in human herpesvirus-6-associated acute encephalopathy/febrile seizures

Adult onset subacute sclerosing panencephalitis: clinical profile of 39 patients from a tertiary care centre.

Subacute sclerosing panencephalitis presenting as rapidly progressive young-onset dementia

HIV-associated neuro-cognitive disorder EBV: primary CNS lym-phoma JC virus: PML [not equal to] Prions: spongiform ence- phalopathy Spinal Acute viral HIV-1 vacuolar cord myelitis myelopathy ADEM * HTLV-1 myelopathy * Acute disseminated encephalomyelitis [dagger] Subacute sclerosing panencephalitis [not equal to] Progressive multifocal leucoencephalopathy.

Viral infections of the central nervous system: viral infections of the CNS are caused by a broad range of viruses

It has been shown that MV induces mitochondrial structural abnormalities in dendrites during persistent infection of the brain termed subacute sclerosing panencephalitis (SSPE)28 and also has been associated with apoptosis.

Effect of measles virus (MV) on mitochondrial respiration

Susanne Prendergast got measles when she was just two - but it was eight years before she started to show signs of the rare measles-relatebrain disorder Subacute Sclerosing Panencephalitis in the summer of 1982.

'We were told it was just measles and it would go.. months later Naomi was given no chance to live' Two dads tell of their heartache

Some sufferers have even been known to develop a progressive and fatal brain infection known as subacute sclerosing panencephalitis, which may not develop until years after the bout of measles.

What every parent must know; SUNDAY FOCUS: Facts be e hind Wales' measles crisis

Subacute sclerosing panencephalitis with atypical onset: Clinical, computed tomographic, and magnetic resonance imaging correlations.

Atypical onset subacute sclerosing panencephalitis: case report/Atipik baslangicli subakut sklerozan panensefalit: olgu sunumu

Jack's disease - subacute sclerosing panencephalitis - is slowly killing him.

JACK IS READY TO HIT THE OPEN ROAD

As mentioned, measles virus is known to cause persistent infections in the brain that can lead to subacute sclerosing panencephalitis and "measles virus inclusion body encephalitis." [41] A correlation between Paget's disease and measles virus infection is controversial.

Persistent measles virus infection as a possible cause of otosclerosis: State of the art

INTRODUCTION: Subacute sclerosing panencephalitis (SSPE) is a slow progressive degeneration of the central nervous system caused by a persistent defective measles virus infection.