Diabetics should always carry 300mg soluble Disprin, on feeling symptoms of ischemic heart disease or stroke, they should immediately take it sublingually
and report to hospital.
With a view to ensuring the efficiency of provocative testing, the treatment with such vasodilators as calcium antagonists and nitrates should be stopped 48 hours before the procedure, being allowed only if administration of nitroglycerin sublingually
is necessary (JCS Joint Working Group 2010).
The sufentanil pharmacokinetic profile when delivered sublingually
potentially avoids the high peak plasma levels and short duration of action observed with IV administration.
According to the companies, BHV-0223 is an innovative sublingually
administered and orally dissolving tablet (ODT) formulation of riluzole, a glutamate modulating agent, which is designed to advance beyond the current limitations of riluzole tablets.
The pharmacodynamic ingredients are likely to be directly absorbed through the mucosa into the blood stream when sublingually
administered, avoiding hepatic first-pass effect and degradation by digestive juice in the gastrointestinal tract, and facilitating bioavailability and a rapid relief during emergency condition.
In the approach I take to LDI, the antigen is almost always administered sublingually
The addition of naloxone is designed to prevent diversion and misuse of buprenorphine as it would precipitate opiate withdrawal if injected but not when ingested, because naloxone is poorly absorbed sublingually
In addition to the buds that generally are smoked, available for purchase are vape cartridges, edibles, oils to take sublingually
and topical applications, to name a few.
Allergen extracts administered sublingually
are taken up by dendritic cells in the oral mucosa and presented to T cells in the draining lymph nodes, likely resulting in activation of regulatory T cells and downregulation of mucosal mast cells.
1) Guidelines from the World Health Organization and the International Federation of Gynecology and Obstetrics reflect the latest evidence and clearly recommend the evidence-based regimen of 800 pg misoprostol sublingually
for treatment of PPH, (2) which has been shown to be comparable to 40 IU oxytocin intravenously in women who receive oxytocin for PPH prophylaxis.
Misoprostol can be given orally, sublingually
, vaginally or rectally.
The IV Free MKO Melt (midazolam, ketamine and ondansetron) compounded conscious sedation formulation is an alternative option to IV anesthetic that is administered sublingually
to sedate patients undergoing ocular and other surgical procedures.