Similar to tirasemtiv and reldesemtiv, the next-generation FSTA from a distinct chemical series, being developed in collaboration with Astellas for the potential treatment of neuromuscular diseases of impaired muscle function, CK-2066260 binds directly to fast skeletal muscle troponin, increases myofibrillar calcium sensitivity and amplifies the force response to submaximal
Examining PAP in the endurance phenotype, a widely cited article by Sale (2004) suggests that PAP should have its greatest effect during submaximal
contractions in which the motor units are firing at relatively lower frequencies, as is the case with endurance exercise.
exercise, muscular contraction and power) are unaffected by fasting.
Cardiorespiratory fitness was measured using a submaximal
cycle test and expressed as maximal oxygen uptake (VO2 max) in ml/minute/kg body weight.
They also completed a submaximal
treadmill stress test that estimated their current endurance capacity.The researchers originally were most interested in that last measurement.
"Surprisingly, push-up capacity was more strongly associated with cardiovascular disease risk than the results of submaximal
In addition, push-up capacity was more strongly associated with lower incidence of cardiovascular disease events than was aerobic capacity as estimated by a submaximal
treadmill exercise test.
 Muscle endurance, by definition, is the ability of a muscle to sustain a submaximal
load for a period of time, according to the American College of Sports Medicine guidelines.
This study compares the change in serum levels of IL-15 in obese and non-obese after a single session of submaximal
It is a submaximal
version which is also a very useful test to see the development".
and maximal methods were found to be linked to excellent reliability of EMG recordings (Oskouei et al., 2013).
These included wrist-worn accelerometers (for example, Fitbit-type wristbands), hand dynamometers (used for grip strength) and submaximal