substantia gelatinosa


Also found in: Medical, Wikipedia.
Related to substantia gelatinosa: Nucleus proprius

sub·stan·ti·a ge·lat·i·no·sa

 (səb-stăn′shē-ə jə-lăt′n-ō′sə)
n.
A narrow, dense, vertical band of gray matter forming the dorsal part of the posterior column of the spinal cord whose gelatinous appearance is due to its very low content of myelinated nerve fibers. It functions in the integration of sensory stimuli that give rise to the sensations of heat and pain.

[New Latin substantia gelatinōsa : Latin substantia, substance + New Latin gelatinōsus, gelatinous.]
References in periodicals archive ?
The greatest concentrations of kappa-receptors in nociceptive regions are in lamina I and II of the spinal cord dorsal horn as well as in the spinal nucleus of the trigeminal nerve (substantia gelatinosa).
Lamina II of the dorsal horn (substantia gelatinosa) is a major target of nociceptive primary afferents.
Fentanyl showed its effect in substantia gelatinosa that is in dorsal horn of spinal cord blockade is done with inhibition of neuronal excitation in both pre-synaptic and post-synaptic levels.
The substantia gelatinosa (SG) of the dorsal horn is the first site of synaptic transmission in the nociceptive pathway, and it is an area vital for the integration and modulation of the peripheral nociceptive input.
The impulse travels to the dorsal horn of the spinal cord, and the noxious stimulus is allowed to reach upper levels of the Central Nervous System only when substantia gelatinosa cells are stimulated.
N-type calcium channels are located mainly in the dorsal horn cells of the spinal cord, predominantly on the superficial layers, in the area of substantia gelatinosa where pain fibers synapse, Dr.
The enkephalins are found mainly in those areas of the brain associated with pain control, including the periventricular area, the periaqueductal gray, the midline raphe nuclei, the substantia gelatinosa of the dorsal horns in the spinal cord, and the intralaminar nuclei of the thalamus.
[45] The major site of action of opioid is within the second and third laminae of substantia gelatinosa in the dorsal horn of the spinal cord.
Due to concentrated small neurons and their processes plus a relative small number of myelinated axons, the lamina II is observed as a translucent band under the naked eye or light microscope and is called "substantia gelatinosa (SG)" [4, 6].
Antinociceptive effect is also produced at the spinal cord level by action at the substantia gelatinosa inhibiting the release of substance P and glutamate.
Safronov, "Excitatory interneurons dominate sensory processing in the spinal substantia gelatinosa of rat," Journal of Physiology, vol.
Full browser ?