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Related to subtilisin: trypsin


Any of several extracellular enzymes produced by bacteria of the genus Bacillus that catalyze the breakdown of proteins into polypeptides and are widely used in detergents and cleaning products.

[New Latin (Bacillus) subtīlis, bacterial species to which were assigned the bacteria from which a subitilisin was first isolated (now known to be B. amyloliquefaciens); see subtilin + -in.]


any of various protease enzymes originally derived from Bacillus subtilis
References in periodicals archive ?
Insurance approval rates for pro-protein convertase subtilisin / kexin type 9 inhibitors are strikingly low, according to a study published in Circulation.
PCSK9 stands for "Proprotein Convertase Subtilisin Kexin (9).
Within the field of lipid metabolism, the rapid clinical development of proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors to reduce LDL cholesterol provides proof-of-concept for the potential of this approach.
The RXRR sequence has been predicted as a consensus sequence in the Vtg protein for the recognition site by furin, a proprotein-converting enzyme that is structurally related to bacterial subtilisin (Hosaka et al.
Enter a new class of drugs--proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors--which, according to a Cleveland Clinic expert, have the potential to change the landscape of LDL management and, possibly, cardiovascular risk reduction.
To do this they are developing injectable monoclonal antibodies against a newly discovered protein known as proprotein convertase subtilisin kexin 9, which dramatically reduces the amount of LDL cholesterol circulating in the bloodstream.
solani isolate from tomato in medium, containing heat-stable potato proteins, due to the presence among these proteins of a large amount trypsin and subtilisin inhibitors [34, 35].
Characterization of a bifunctional wheat inhibitor of endogenous a-amylase and subtilisin.
Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis.
The important detergent enzymes, subtilisin Novo or BPN [30] also showed maximum activity at pH 10.
Other inhibitors like wheat protease inhibitor can inhibit both subtilisin and chymotrypsin (Di Gennaro et al.