Detection of various Organic acids (OA) and their metabolites is the key to the diagnosis of not only organic acidemias, but through testing of certain metabolites like homogentisic acid, orotic acid and succinyl
acetone, a range of conditions like homocystinuria, ornithine transcarbamoylase deficiency, and tyrosinemia Type-12, can be detected on this panel.
On stratification by type of disorders leading to methylmalonic acidurias, 9(22%) had methylmalonic acidemia, 12(29%) had Cobalamin-related remethylation disorders, nonspecific methylmalonic acidurias in 16(39%), while 2(5%) each had succinyl
coenzyme A synthetase and Vitamin B12 deficiency.
4-Ferrocenyl phenol (0.5 g, 1.80 mmol), 10 mL THF, 10 mL triethylamine and succinyl
chloride (0.18 g, 1 mmol) were made to react to procure E8.
CoA is subsequently incorporated into part of the tricarboxylic acid cycle to generate OAA .
A potential "cocaine vaccine" called TA-CD, which is made from succinyl
norcocaine conjugated to cholera toxin, is being evaluated.
Toxic metabolites and their derivates such as FAA, maleylacetoacetate, succinyl
acetoacetate and succinyl
acetone (SA) play a major role in tissue damage with hepatic, renal and neurological findings.
Familial/syndromic cases are seen in specific hereditary succinyl
dehydrogenase mutations (SDH-B, C & D), Carneys complex and Neuro-fibromatosis.
The authors  propose corn and amaranth starch modification from octane succinyl
derivatives in order to improve the emulsification properties and to use in encapsulation.
We report the case of a 65-year-old man known for hypertension, cholelithiasis, and panic disorder with no personal or family history of pheochromocytoma, paraganglioma, Multiple Endocrine Neoplasia Type 2 syndrome, Von Hippel Lindau syndrome, Neurofibromatosis Type 1, or Succinyl
Wells of 96-well microtiter plates were incubated with 100 [micro]L of 1 mg/ml autologous human IgG, ConA, succinyl
ConA (SConA), wheat germ agglutinin (WGA), and protein-free DPBS.
Heme is synthesized from glycine and succinyl
CoA via an eight-step pathway, with each step being catalyzed by a separate enzyme.