sulfinpyrazone


Also found in: Medical, Wikipedia.

sul·fin·pyr·a·zone

 (sŭl′fĭn-pĭr′ə-zōn′)
n.
A drug, C23H20N2O3S, related to phenylbutazone, that promotes urinary excretion of uric acid and is used in the treatment of gout.

References in periodicals archive ?
A Randomized Trial of Aspirin and Sulfinpyrazone in Threatened Stroke.
The formation of uric acid from purines may be reduced with xanthine-oxidase inhibitors allopurinol or febuxostat, or the use of uricosuric drug sulfinpyrazone to increase the excretion of uric acid within urine.
A sixth agent, sulfinpyrazone (Anturane), a uricosuric agent, has been withdrawn from the market, but there are no reports describing its use to treat gout in pregnant women.
Myers, Cairns, and Singer examined gastrointestinal side effects in a multicenter trial of aspirin or sulfinpyrazone in the treatment of unstable angina.
28) This protein is the target for most uricosuric drugs, including probenecid, sulfinpyrazone, benzbromarone, and high-dose salicylates, as well as minor uricosurics, such as losartan.
Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons.
Sulfinpyrazone, propranolol, ranitidine, salbutamol, enalapril and lovastatin are some of the precedents spanning this time period.
In addition to aspirin, sulfinpyrazone and ticlopidine were included in the analysis of related drugs.
2] blockers, magnesium salts, methyldopa, MAO inhibitors, phenylbutazone, probenecid, salicylates, sulfinpyrazone, sulfonamides, tricyclic antidepressants, and urinary acidifiers.
Sulfinpyrazone use is problematic, given its side effects and drug interactions, and sulfinpyrazone is not universally available.