sulphonyl


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Related to sulphonyl: sulfinyl

sulphonyl

(ˈsʌlfənɪl)
n
(Chemistry) (modifier) another term for sulphuryl
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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In present study we reported the synthesis of benzoyl and sulphonyl derivatives by taking Piperidine-4-carboxamide as principal molecule.
Both 33DDS and 44DDS isomers have the same electron withdrawing sulphonyl group, where the only difference comes from the orientation of the N[H.sub.2] groups.
Thirty experimental animals were fasted for 12 h and grouped as follows: group 1 (control), treated with isotonic saline solution (ISS, 4 mL/kg); group 2, treated with the fat fraction (16 mg/kg); group 3, treated with the protein fraction (16 mg/kg); group 4, treated with the chitin fraction (16 mg/kg); and group 5, positive control, treated with glibenclamide (10 mg/kg), a sulphonyl urea agent with hypoglycemic action that acts at the pancreatic level as an insulin secretagogue.
The sulphonyl moiety of glutathione sulfonate positioned towards the C-terminal domain of the same subunit and the Gly moiety of the glutathione sulfonate located above third beta sheet ([beta]3) (Fig.
Wilhelm N, Holloway RE (1998) Persistence of sulphonyl urea herbicides on alkaline soil.
It binds to 65 kD protein on [beta]-cells, which appears to be a part of the same sulphonyl urea receptor that binds Glibenclamide.
Briefly, mice kidneys were homogenized at 10% (w/v) in a Potter Elvehjem homogenizer (Wheaton, NJ, USA) using a homogenization buffer containing 20 mM HEPES, pH 7.9, 1mM Mg[Cl.sub.2], 0.5 mM EDTA, 1mM EGTA, 1mM dithiothreitol (DTT), 0.5 mM phenylmethyl sulphonyl fluoride (PMSF), and 1 ul/ml PIC.
It is sulphonyl urea group type of herbicide, and is composed of 10.1% metsulfuron methyl, 10.1% chlorimuron ethyl and remaining 79.80% adjuvants [1].
In other sets of experiments, the stimulated RAW 264.7 cells were washed with phosphate buffer solution (PBS, 137 mM NaCl, 2.7 mM KC1, 2 mM K[H.sub.2]P[O.sub.4], 10 mM [Na.sub.2]HP[O.sub.4], pH 7.4) and lysed in an ice cold radio immunoprecipitation assay (RIPA) buffer (TrisHC1, pH 7.2, 25mM;0.1% sodium dodecyl sulphate (SDS); EDTA; 1% Triton X-100; 1% sodium deoxycholate; 0.15 M NaCl) containing 1 mM phenylmethyl sulphonyl fluoride (PMSF), 10 [micro]g/ml aprotinin, 1 mM sodium orthovanadate, and 5 [micro]g/ml leupeptin.
This observation suggests that coordination of metal with ligand does not occur through sulphonyl oxygen.