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A structure of a helix, especially a DNA molecule, in which the axis of the helix itself is coiled, causing the helix to loop over itself.
intr.v. su·per·coiled, su·per·coil·ing, su·per·coils
To form a supercoil.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˈsuːpəˌkɔɪl) biochem
a coil consisting of coils, a complex coil; particularly, a superhelical structure of DNA
to make into or become a complex coil
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈsu pərˌkɔɪl)

a twist formed by intertwining strands of DNA or by protein chains.
su′per•coiled`, adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
Unwinding leads to positive and negative DNA supercoils. Topoisomerases reduce these supercoils by cutting and re-ligating either single or both strands.
Transcription elongation is accompanied by changes in the local supercoiled state of DNA, forming positive supercoils ahead and negative super-coils behind the transcriptional machinery [197, 198, 216, 217].
Under alkaline conditions, the negatively charged DNA supercoils with broken ends were able to migrate toward the anode during electrophoresis.
The compaction of DNA helices into either continuous supercoils or folded-fiber rods and toroids.
Topoisomerase IV lacks the ability to introduce negative supercoils into DNA, a function that is unique to DNA gyrase.
This step-by-step guide shows you how to create 80 distinctive yarns, from classics such as mohair boucle to novelty features like supercoils.
Comet assay, also known as single cell gel electrophoresis (SCGE), is based on a principle that when the sperm DNA breaks, DNA supercoils become loose and the negative charges are exposed.
"The Spinner's Book of Yarn Designs: Techniques for Creating 80 Yarns" is described as "the first definitive step-by-step guide to creating a full repertoire of yarn styles," including classic cable yarns and novelty supercoils. An inspiring foreword by expert spinner Judith MacKenzie prepares readership for a magical journey through the wonders of spinning yarn, pointing out that new fibers have been created that never existed before.
DNA gyrase is the enzyme that unwinds the double-stranded DNA and topoisomerase IV decatenates DNA following replication relaxing positive supercoils. There are three known mechanisms of resistance to quinolones.
For DNA gyrase, this topoisomerization reaction results in introduction (or removal) of DNA supercoils, thus affecting the negative supercoiling of DNA necessary to initiate DNA replication and remove positive supercoils that accumulate before an advancing replication fork.
Then they bend and twist again, folding into gnarled supercoils.
The size of the Supercoils makes them suitable for use in cooling metal-plating baths.