tRNA


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Related to tRNA: rRNA, suppressor tRNA

tRNA

abbr.
transfer RNA

transfer RNA



n.
any of a class of small, cloverleaf forms of RNA that transfer unattached amino acids in the cell cytoplasm to the ribosomes for protein synthesis.
Abbr.: tRNA
[1960–65]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tRNA - RNA molecules present in the cell (in at least 20 varieties, each variety capable of combining with a specific amino acid) that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell (according to directions coded in the mRNA)tRNA - RNA molecules present in the cell (in at least 20 varieties, each variety capable of combining with a specific amino acid) that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell (according to directions coded in the mRNA)
ribonucleic acid, RNA - (biochemistry) a long linear polymer of nucleotides found in the nucleus but mainly in the cytoplasm of a cell where it is associated with microsomes; it transmits genetic information from DNA to the cytoplasm and controls certain chemical processes in the cell; "ribonucleic acid is the genetic material of some viruses"
References in periodicals archive ?
2]-modification status as a direct marker for investigating CD KALI enzyme activity in human samples and its association with T2D risk; however, current methods of measuring site-specific tRNA modifications, such as mass spectrometry and the primer-extension method (6, 10), are not applicable to clinical samples, for several reasons.
The E Site is the exit site for the tRNA anticodon once it deposits its amino acid from the cytoplasm onto the growing polypeptide chain.
The recent finding that BMAA is mistaken for serine by tRNA synthetase during; protein formation opens up a plethora of potential new studies in lab models of ALS, from yeast to mice, to see whether the formation of procein aggregates--the classic 'hallmarks' of motor neuron degeneration-- can be replicated," says Brian Dickie, director of research at the Motor Neurone Disease Association.
The privately held biotech was founded by Scripps Research Institute Professor Paul Schimmel, a leading aminoacyl tRNA synthetase scientist, and is backed by top life sciences investors Alta Partners, Cardinal Partners, Domain Associates and Polaris Ventures.
An expert on tRNA synthetases, Paul Schimmel has also been the co-founder or founding director of numerous successful biotechnology companies, including Sirtris Pharmaceuticals, Alnylam, Repligen Corporation, Alkermes, Inc.
It was Tzvetkova who showed that this chemical mimic will allow an amino acid to attach to the complex tRNA molecule in just the right place.
They then tested billions of slightly different enzymes to find ones that would attach the tRNA to the three kinds of synthetic amino acids used in the study.
vagans tRNA sequences were identical across all 22 individuals, and had a higher AT composition (75.
Most pathogens responsible for causing infectious diseases -- including HIV, the virus that causes AIDS -- require tRNA for replication.
Transcription of mRNA and transfer of the amino acids by specific tRNA are vital steps in cellular protein synthesis on the surface of ribosomes.
Nuclear magnetic resonance (NMR) structures of the third human tRNA that codes for lysine indicates that the inclusion of the posttranscriptionally modified base threonylcarbamoyladenosine at position 37 ([t.