tamoxifen


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Related to tamoxifen: Nolvadex, Tamoxifen citrate

ta·mox·i·fen

 (tə-mŏk′sə-fĕn)
n.
A drug that is a selective estrogen receptor modulator, C26H29NOS, used in the form of its citrate primarily to treat breast cancer in women whose tumors are estrogen-dependent and to prevent breast cancer in high-risk women.

[t(rans)- + am(ino)- + alteration of oxy- + alteration of phen(ol).]

tamoxifen

(təˈmɒksɪfɛn)
n
(Pathology) a drug that antagonizes the action of oestrogen and is used to treat breast cancer and some types of infertility in women
[C20: altered from t(rans-) + am(ine) + oxy-2 + phen(ol)]

ta•mox•i•fen

(təˈmɒk sə fən, -ˌfɛn)

n.
a drug, C26H29NO, that blocks the estrogen receptors on cancer cells, used to treat breast cancer and to prevent recurrence or occurrence of breast cancer in high-risk people.
[1970–75; perhaps t (rans)- + am (ino)- + oxy-2 + phen (yl), with resp. of y and ph]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tamoxifen - an antagonist for estrogen that is used in the treatment of breast cancer
antagonist - a drug that neutralizes or counteracts the effects of another drug
Translations

tamoxifen

n tamoxifeno
References in periodicals archive ?
The various side effects of tamoxifen therapy appear to be age dependent.
In women diagnosed with breast cancer, taking tamoxifen and/or aromatase inhibitors reduces the risk of developing cancer in their other breast, according to a study published online Oct.
com)-- Tamoxifen is an antagonist of the estrogen receptor in breast tissue.
SAN DIEGO -- Researchers at the University of California, San Diego, School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiments.
SAN ANTONIO -- Adding ovarian suppression to 5 years of tamoxifen in women with hormone receptor-positive early breast cancer who remain premenopausal following chemotherapy provides a markedly greater reduction in breast cancer recurrence, compared with standard adjuvant therapy with tamoxifen alone--and combining ovarian suppression with an aromatase inhibitor instead of tamoxifen further improves outcomes, Dr.
Tamoxifen (trade name Nolvadex) has been hailed as a 'wonder drug' by many physicians (and patients) since it's inception in the 1970's.
In most tamoxifen research, the studies have lasted for a period of five years, although some benefits continue in years 5 to 10.
Women who have hormone-sensitive breast cancer and who have taken tamoxifen for 5 years as adjuvant therapy stand to benefit from an additional 5 years of the drug, according to preliminary findings from the Adjuvant Tamoxifen: Longer Against Shorter (ATLAS) trial.
London, December 6 ( ANI ): Breast cancer deaths can be halved if patients are treated with drug Tamoxifen for 10 years, a new study has revealed.
Tamoxifen's most abundant metabolite, endoxifen, has a much greater affinity for the estrogen receptor than does tamoxifen itself, and is generally considered to be the primary compound responsible for clinical benefit.
ALMOST 40 years after Welsh research discovered the potential of tamoxifen, a new study has found the breast cancer drug can dramatically increase long-term survival.
Breast cancer patients who struggle with the side effects of long-term tamoxifen therapy have an encouraging discovery to consider.