The various side effects of tamoxifen
therapy appear to be age dependent.
In women diagnosed with breast cancer, taking tamoxifen
and/or aromatase inhibitors reduces the risk of developing cancer in their other breast, according to a study published online Oct.
is an antagonist of the estrogen receptor in breast tissue.
SAN DIEGO -- Researchers at the University of California, San Diego, School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen
gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiments.
SAN ANTONIO -- Adding ovarian suppression to 5 years of tamoxifen
in women with hormone receptor-positive early breast cancer who remain premenopausal following chemotherapy provides a markedly greater reduction in breast cancer recurrence, compared with standard adjuvant therapy with tamoxifen
alone--and combining ovarian suppression with an aromatase inhibitor instead of tamoxifen
further improves outcomes, Dr.
(trade name Nolvadex) has been hailed as a 'wonder drug' by many physicians (and patients) since it's inception in the 1970's.
In most tamoxifen
research, the studies have lasted for a period of five years, although some benefits continue in years 5 to 10.
Women who have hormone-sensitive breast cancer and who have taken tamoxifen
for 5 years as adjuvant therapy stand to benefit from an additional 5 years of the drug, according to preliminary findings from the Adjuvant Tamoxifen
: Longer Against Shorter (ATLAS) trial.
London, December 6 ( ANI ): Breast cancer deaths can be halved if patients are treated with drug Tamoxifen
for 10 years, a new study has revealed.
's most abundant metabolite, endoxifen, has a much greater affinity for the estrogen receptor than does tamoxifen
itself, and is generally considered to be the primary compound responsible for clinical benefit.
ALMOST 40 years after Welsh research discovered the potential of tamoxifen
, a new study has found the breast cancer drug can dramatically increase long-term survival.
Breast cancer patients who struggle with the side effects of long-term tamoxifen
therapy have an encouraging discovery to consider.