tardive dyskinesia


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Related to tardive dyskinesia: neuroleptic malignant syndrome, tardive dystonia

tardive dyskinesia

n.
A chronic disorder of the nervous system characterized by involuntary jerky movements of the face, tongue, jaws, trunk, and limbs, usually caused by prolonged treatment with antipsychotic drugs.

tar′dive dyskine′sia


n.
nerve damage resulting in involuntary rolling of the tongue or twitching of facial or other small muscles, usu. associated with long-term use of antipsychotic drugs.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tardive dyskinesia - involuntary rolling of the tongue and twitching of the face or trunk or limbs; often occurs in patients with Parkinsonism who are treated with phenothiazine
dyskinesia - abnormality in performing voluntary muscle movements
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References in periodicals archive ?
Several case reports of orofacial tardive dyskinesia have found improvements in hyperkinetic movements following BTA injections
Tardive dyskinesia in children treated with atypical antipsychotic medications.
The theme of the competition this year concerning tardive dyskinesia is timely and consistent with the mission of NMSIS to promote knowledge on neurologic side effects of antipsychotic drugs.
[3, 4] In addition, some patients may have gastrointestinal tardive dyskinesia which causes symptoms, such as discomfort in the stomach, nausea and vomiting.
Other extrapyramidal symptoms that developed in adults were chronic reactions including parkinsonism [3, 4] or tardive dyskinesia [4].
As Tardive dyskinesia is frequently associated with first generation neuroleptics, these medications should be used restrictively only in major mental disorder and also doses should be kept low.
Tardive dyskinesia: a task force report of the American Psychiatric Association.
This report provides comprehensive information on the therapeutic development for Tardive Dyskinesia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
Topline results for Auspex's Phase III ARM-TD study of SD-809 as a potential treatment for tardive dyskinesia, a disorder for which there are no approved therapies, are also expected in mid-2015.
Morningside's investment in Synchroneuron demonstrates our belief in the potential of SNC-102 to safely and effectively treat neuropsychiatric disorders such as tardive dyskinesia as well as its potential in additional indications, said Gerald Chan, Chairman of Morningside Technology Ventures.
Moreover, there is evidence that abnormalities of 5-HT functions are related to the pathophysiology of diverse neurological conditions including Parkinson's disease, tardive dyskinesia, akathisia, dystonia, Huntington's disease, familial tremor, restless legs syndrome, myoclonus, Gilles de la Tourette's syndrome, multiple sclerosis, sleep disorders, and dementia.
A literature survey reveals that the Pro 197 Leu GSH-Px gene polymorphism has been studied in schizophrenics and patients who developed tardive dyskinesia due to drugs while it has not been studied in patients with mood disorders.