target cell


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Related to target cell: poikilocytosis, basophilic stippling

target cell

n.
1. A cell selectively affected by a particular agent, such as a virus, drug, or hormone.
2. An abnormal red blood cell having a dark center surrounded by a light band that is itself encircled by a darker ring, seen in certain anemias and after splenectomy.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.target cell - any cell that has a specific receptor for an antigen or antibody or hormone or drug, or is the focus of contact by a virus or phagocyte or nerve fiber etc.
somatic cell, vegetative cell - any of the cells of a plant or animal except the reproductive cells; a cell that does not participate in the production of gametes; "somatic cells are produced from preexisting cells";
2.target cell - an abnormal red blood cell with the appearance of a dark ring surrounding a dark center; associated with anemia
erythrocyte, RBC, red blood cell - a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus
References in periodicals archive ?
The LNP is designed to deliver its non-integrating DNA payload to solid tumors, while an engineered promoter drives expression of a potent, inducible death protein only in the target cell population.
Currently available electroporation equipment is tailored to fit different types of applications depending on the researcher's target cell or tissue types.
It will use a novel and replication deficient lentiviral vector in an inhaled formulation to selectively introduce a CFTR gene into the relevant target cell. It is also planning to assess Oxford BioMedica's transgene repression in vector production system and develop stable producer cell lines for large scale production of the lentiviral vector.
These microbubbles bear antibodies on their surface, enabling them to bind specifically to a single desired target cell type.
Stability of the Recombinant Effector and Target Cell Lines.
In the current study, researchers report on a new class of drug-like molecules that exploit our increasingly nuanced understanding of another facet of apoptosis regulation to specifically target cell death in cancer cells--work which has the potential to further expand our armamentarium of drugs to fight neoplastic disease."
Killers perform their functions either from a distance or when in contact with the target cell. The cytotoxic effect of killers is realized in the target cell plasma membrane by special proteins--perforins, granzymes, etc., which lead to the formation in this organoid of perforations (pores).
MPs alter target cell function, for example, MPs isolated from diabetic patients have pro-thrombotic effects on target cells [2].
"We know that enveloped viruses must fuse their membrane with the target cell membrane in order to initiate infection, and blocking this step can prevent or treat infection, as has been clinically validated for HIV virus."
Nevertheless, it has been shown that CB-derived NK and lymphokine-activated killer cells are able to lyse non-cultured fresh leukemia blasts, readily respond to IL-2 and IL-12, and mediate relatively high levels of apoptosis-mediated cytotoxicity against target cell lines (18), (19).
* Different hormones can exert the same or different actions on the same target cell.
Different cell volume with high target cell population between liver disease and homogygous hemoglobin E.