The Canadian patent covers the capture of target cells
, including CTCs, using a combination of binding partners and methods for capture on any surface.
T cell engagers are engineered proteins that direct a patient's own T cells to kill target cells
that express specific proteins, or antigens, carried by the target cells
CDX binds to the FLT3 protein, which is found on the surface of target cells
, and to the CD3 protein on the surface of immune cells called T-cells, redirecting T-cells to kill target cells
"The system can separate the target cells
among a number of cells and it is also able to isolate molecular samples labeled with magnetic particles," Moayyed Dehqanpour, the manager of Sepid Jamegan, said on Tuesday.
* The target cells
and tissues to which researchers may deliver CRISPR gene-editing tools will continue to expand by using more sophisticated transfection techniques such as electroporation.
The company said the ClearCell FX1 System is a leading, automated, label-free liquid biopsy device for the enrichment of target cells
Patent and Trademark Office issued a patent to Cesca Therapeutics for a method ogf separating rare, therapeutically critical target cells
from blood, bone marrow, leukapheresis product, and other cell sources, while maintaining the viability of the cells under asceptic conditions.
The activity of numerous therapeutic antibodies is mediated in part by immune-mediated effector cell function following binding of the variable regions of the antibody to a specific antigen on the surface of target cells
and the interaction of the Fc moiety of the antibody with an Fc receptor on an immune effector cell .
According to a statement published on the MIT website Thursday, the method its researchers have developed allows Crispr to be used only when ultraviolet light is shone on the target cells
, effectively making the light a switch.
QuickGel dissolvable hydrogel technology enables high efficiency purification and release of target cells
. Delivering improved cell viability, purity and recovery, QuickGel overcomes limitations of other cell capture chemistries and enables researchers to simplify their cell separation workflows.
According to the tests, this system significantly decreases the side effects of daunorubicin drug in the control cells, and it increases its therapeutic effects in the target cells
in comparison with the drug without carriers.