Hypertensive children should be assessed for target organ
damage, which can affect the heart, retina, kidneys and nervous system.
In order to approach the ambitious task of mapping mechanisms specific for these potential target organs
, a three-step approach was taken to identify the potential pathways of target organ
Kidneys are the target organ
of hypertension, as well as the initiating organ of renal hypertension, and hypertension is related to the occurrence and progression of CKD (Bloomfield et al., 2013; Zheng et al., 2013).
The study showed that acute or worsening heart failure was the most frequent target organ
injury (49.6 per cent) followed by non-ST elevation myocardial infarction-type of heart attack (41.7 per cent).
"Carefully selected interventions that improve patients' adherence to medications, and strategies that help providers to overcome clinical inertia, or a failure to increase therapy when blood pressure goals are unmet, may potentially reduce target organ
damage associated with hypertensive emergencies." ( ANI )
Evaluation should then include identification of contributing lifestyle issues, detection of drugs interfering with antihypertensive medication effectiveness, screening for secondary hypertension, and assessment of target organ
To look for evidence of target organ
damage in hypertensive patients.
Compared to whites, hypertension in blacks is more prevalent, more severe, has an onset earlier in life, and is linked to a higher burden of target organ
Akoglu, "Association between salt sensitivity and target organ
damage in essential hypertension," American Journal of Hypertension, vol.
If undiagnosed, high blood pressure can lead to"possible target organ
damage in the brain, eyes, heart and kidneys," said study leader Dr.
"It is recommended that echocardiography be performed to assess for cardiac target organ
damage (left ventricular mass, geometry, and function) at the time of consideration of pharmacologic treatment of HTN," they wrote, suggesting repeat echocardiography could be used to monitor target organ
damage at 6- to 12-month intervals.