teratogenicity


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ter·a·to·gen·ic

 (tĕr′ə-tə-jĕn′ĭk)
adj.
Of, relating to, or causing malformations of an embryo or fetus.

ter′a·to·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.
ter′a·to·gen′e·sis (-ĭ-sĭs) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Translations

teratogenicity

n teratogenicidad f
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Valproate, linked to increases in both anatomic and behavioral teratogenicity, was less often prescribed, but nevertheless still prescribed in a considerable proportion of patients in the study, which looked at U.S.
It causes serious diseases, such as endocrine and neuropsychiatric disorders, malignancy, and teratogenicity, in the acute and chronic periods.
Of course, teratogenicity is a potential risk that has to be taken very seriously.
Nitrofurantoin and trimethoprim-sulfamethoxazole have study data indicating their teratogenicity, and ACOG has recommended against use of these 2 agents in the first trimester of pregnancy unless other antibiotics are unlikely to be effective.
Conclusion: The study shows that sodium phenytoin exerts an inhibitory effect on the apical ectodermal ridges of developing limbs evident by the decreased number of mitoses in the AER of wing buds of experimental chick embryos making it a potential target site for limb teratogenicity associated with its maternal intake during pregnancy.
ABSTRACT: This study was conducted to evaluate the anti-angiogenic potential and teratogenic effect of the ethanolic extract from Hyptis suaveolens leaves, through chorioallantoic membrane (CAM) vascularity and teratogenicity assays in mallard duck (Anas platyrhynchos) embryos.
Chronic myeloid leukemia (CML) in pregnancy has posed great disparity due to the lack of standard guidelines for its management and concerns regarding effects of teratogenicity. The bcr-abl tyrosine kinase gene mutation, acquired from reciprocal translocation of chromosomes 9 and 22, known as the Philadelphia chromosome, has long been established as the mechanism causing the development of CML.
Shepard's criteria were used to prove teratogenicity, and the Bradford Hill criteria were used to show evidence of causation.
Zebrafish (Daniorerio) embryos have been used as a vertebrate model to study the developmental toxicity and teratogenicity of certain of chemical compounds.
In spite of the clinical benefits, there is a severe teratogenic risk associated with its use during pregnancy and despite continued warnings, the risk of foetal exposure to RA remains high.2,3 Animal studies along with recent epidemiological reports on human teratogenicity raise concerns about the potential for induction of defects in offspring of women of child-bearing age.
Teratogenicity test of dimethoate containing insecticide formulation and Cd-sulphate in chicken embryos after administration as a single compound or in combination.