termination codon


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Related to termination codon: stop codon, Amber codon, opal codon

termination codon

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In our study, the mutation type was insertion/duplication in which one base pair duplication leads to alteration of aspartic acid to glutamic acid in codon 112 and subsequently frame-shift mutation occurs which introduces a Premature Termination Codon (PTC).
49 kDa protein composed of 255 amino acids, containing one initiation codon ATG and one termination codon TAA.
This mutation results in the production of a premature termination codon (tryptophan[right arrow]stop codon) and gives rise to ([[beta].
4 Notwithstanding intron retention potentially affects mRNA transport to the cytoplasm5 and can insert a premature termination codon (PTC) and hence its degradation by the terminator (Non-sense mediate mRNA decay),6 there is an evidence for mRNAs that containing intron and are encoding biologically active proteins.
C T(R255)X Normal findings Mutation description Exon 8 causing an Heterozygous deletion immediate termination of the A nucleotide in codon exon 17 Effect on protein Termination codon A frameshift leading leading to a truncated to a termination codon nonfunctional Rb and truncated, protein nonfunctional Rb protein Abbreviation: Rb, retinoblastoma.
Hemoglobin Constant Spring and Hb Paske both affect the termination codon 142, changing it to an amino acid producing an extended protein product that becomes the target of intracellular proteolytic cleavage.
These alterations included a deletion of 29 nt starting at the 13th position from the ORF termination codon (Figure 1).