thalassemia major


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Noun1.thalassemia major - a fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged
Mediterranean anaemia, Mediterranean anemia, thalassaemia, thalassemia - an inherited form of anemia caused by faulty synthesis of hemoglobin
References in periodicals archive ?
In contrast, beta thalassemia major (Cooley's anemia) is caused by homozygous beta-zero mutations.
Results from the SPARC (A Randomized Controlled Study to Evaluate Efficacy and Safety of S-303 Treated Red Blood Cells in Subjects with Thalassemia Major Requiring Chronic RBC Transfusion) study provide important clinical data regarding the safety profile of Intercept-treated RBCs in a chronically transfused patient population and support Cerus' Intercept RBC CE mark submission, which is planned for the second half of 2018.
Uquali announced to bear the outlay of a Thalassemia major patient from his personal profit for a whole of his life adding that the provision of the funds to Thalassemia Center Badin for solar lights from the fund generated through street gain campaign was an exemplary service of Sindh Doctors Association of UK.
She said the best strategy is to put in full efforts in the prevention of Thalassemia major.
Fetuses affected with thalassemia major can be aborted before 18 weeks of gestational age according to 1998 law permission (6).
asymptomatic and affected can survive without any treatment, thalassemia major i.
12 -- Narayana Health City treats four Sri Lankan children suffering from thalassemia major, a life-threatening disorder, through unrelated donor bone marrow transplant.
Study conducted at Fatima Jinnah Medical College Lahore by Majeed17on family members of Thalassemia Major patients showed a frequency of 52% for beta thalassemia trait with female population of 51.
The patients selected for the study were diagnosed as beta thalassemia major according to hemoglobin electrophoresis.
Thalassemia syndromes included thalassemia minor ([alpha]-thalassemia heterozygote, [beta]-thalassemia heterozygote, and hemoglobin [Hb] E heterozygote), thalassemia intermedia (Hb H disease, Hb H disease with Constant Spring, AE Bart disease, and EF Bart disease), and thalassemia major (homozygous [beta]-thalassemia and [beta]-thalassemia/Hb E disease).
The participants were informed that at present 125,000 patients of thalassemia major are registered in Pakistan with 44 registered bodies.