thalassemia

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thal·as·se·mi·a

 (thăl′ə-sē′mē-ə)
n.
An inherited form of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of part of the hemoglobin molecule. Also called Mediterranean anemia.

[Greek thalassa, sea + -emia.]

thal′as·se′mic adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

thal•as•se•mi•a

(ˌθæl əˈsi mi ə)

n.
a hereditary anemia marked by the abnormal production of hemoglobin, occurring chiefly in people of Mediterranean origin.
[1932; < Greek thálass(a) sea (alluding to the Mediterranean Sea) + -emia]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.thalassemia - an inherited form of anemia caused by faulty synthesis of hemoglobin
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
hypochromic anaemia, hypochromic anemia - anemia characterized by a decrease in the concentration of corpuscular hemoglobin
Cooley's anaemia, Cooley's anemia, thalassaemia major, thalassemia major - a fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

thal·as·se·mi·a

, thalassanemia
n. talasemia, grupo de diferentes tipos de anemia hemolítica hereditaria encontrada en poblaciones de la región mediterránea y sureste de Asia;
major ______ mayor;
minor ______ menor.
English-Spanish Medical Dictionary © Farlex 2012

thalassemia

n talasemia
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Furthermore, a crucial component in the oxidant susceptibility of the thalassemic RBC is the release of heme and iron from the excessive, unpaired alpha-globin chains [2].
Thalassemic individuals have a reduced MCV, and an MCV of 72 femtoliter (fL or [10.sup.-12] liters) is maximally sensitive and specific for presumptive diagnosis of thalassemia syndromes.
We used the hematologic results to check for the presence of a thalassemic phenotype and then investigated patients with borderline [alpha]-thalassemic erythrocyte data when we detected an abnormal peak that eluted at a high percentage of solvent B in the RPLC analysis (see below).
(7) In a prospective study, during a 12-month period, 10% of the 144 thalassemic patients developed one episode of symptomatic infection with pathogenic phenotypes of Y enterocolitica.
Indeed, the mild thalassemic phenotype observed in compound heterozygotes [[beta].sup.E]/[[beta].sup.-28] from Thai population has indirectly indicated that the -28 mutation is a mild thalassemic allele [18].
Another study reported that thalassemic patients were having low incidence of febrile seizures as compared to general population17.
Conclusion: The study demonstrates hypothyroidism in a significant number of hyper transfused b- thalassemic patients, emphasizing the importance of monitoring thyroid functions in thalassemic patients, particularly in those receiving suboptimal chelation.
et al reported that 71% of children suffering from Thalassemia showed growth retardation.[4] In the present study in children with Thalassemia major, Thalassemic facies was present in 9 children out of 12 [75%].
"Iron overload thalassemic cardiomyopathy: iron status assessment and mechanisms of mechanical and electrical disturbance due to iron toxicity." Can J Cardiol.
Mean age of patients who developed red cell alloimmunization was 11.9 years.Thompson reported on 697 thalassemic patients who had received transfusions.
All cases of thalassemia were excluded from the study as globin chains have been documented to aggregate and deposit in the erythrocyte membrane of thalassemic patients contributing to oxidative stress in addition to excess iron deposition.9 Written informed consent was obtained from all participants of the study.