thalidomide


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tha·lid·o·mide

 (thə-lĭd′ə-mīd′)
n.
A sedative and hypnotic drug, C13H10N2O4, withdrawn from general use after it was found to cause severe birth defects when taken during pregnancy. It is currently used to treat leprosy.

[(ph)thal(ic acid) + (im)id(e) + (i)mide.]

thalidomide

(θəˈlɪdəˌmaɪd)
n
(Pathology)
a. a synthetic drug formerly used as a sedative and hypnotic but withdrawn from the market when found to cause abnormalities in developing fetuses. Formula: C13H10N2O4
b. (as modifier): a thalidomide baby.
[C20: from thallic + -id- (from imide) + imide]

tha•lid•o•mide

(θəˈlɪd əˌmaɪd)

n.
a crystalline, slightly water-soluble solid, C13H10N2O4, formerly used as a sedative: if taken during pregnancy, it may cause severe abnormalities in the limbs of the fetus.
[1955–60; (ph)thal(im)ido(glutari)mide = phthalimide (phthal (ic) + imide) + -o- + glutarimide (glut(en) + (tart)ar(ic) + imide)]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.thalidomide - a sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis
sedative-hypnotic, sedative-hypnotic drug - a sedative that depresses activity of the central nervous system and reduces anxiety and induces sleep
teratogen - any agent that interferes with normal embryonic development: alcohol or thalidomide or X-rays or rubella are examples
Translations

thalidomide

® [θəˈlɪdəʊmaɪd] Ntalidomida f

thalidomide

[θəˈlɪdəmaɪd] nthalidomide fthalidomide baby nenfant mf victime de la thalidomide

thalidomide

n˜ Contergan® nt, → Thalidomid nt; thalidomide babyContergankind nt

thalidomide

® [θəˈlɪdəʊˌmaɪd] ntalidomide ® m

tha·lid·o·mide

n. talidomida, sedativo e hipnótico, causante probado de malformaciones en niños de madres que tomaron la droga durante el embarazo.

thalidomide

n talidomida
References in periodicals archive ?
The Ministry of Health, Social Services and Equality, through the Office of Affected by Thalidomide, created for this purpose in the Carlos III Health Institute, enables the dissemination Portal and the Collaborative Platform that will serve so that the Diagnostic Units of each Autonomous Community, the Scientific / Technical Committee and the group of experts define if a person has been really affected by Thalidomide.
We present an eight-year-old boy having recalcitrant bullous pyoderma gangrenosum treated successfully with thalidomide.
The mother of one is also a lead campaigner for Thalidomide Memorial, which aims to mark the lives and achievements of thalidomide-impaired people in the UK and honour those who worked to secure justice for them.
A CEREMONY will take place today to mark the first anniversary of the unveiling of Wales' Thalidomide Memorial.
4) Thalidomide is effective but associated with side effects including tiredness, constipation and neuropathy.
Background: Thalidomide is an immunomodulatory and anti-angiogenic drug that has shown promise in patients with myeloma.
A THALIDOMIDE storyline in TV's Call the Midwife could help survivors of the tragedy who are still fighting for compensation, bosses believe.
Thalidomides are also capable of modulating the function of key element of the immune system related to the pathogenesis of MS, but this brief article is intended to emphasise the potential of thalidomide and its analogues as potent inhibitors of angiogenesis and the latent possibility of their use as a therapeutic agent in the control of MS.
A THALIDOMIDE victim who went on to earn a degree, have a child and is soon to be married, has spoken of how a very special teacher changed his life forever.
Iimagine that most people will have heard of Thalidomide.
Thalidomide survivors say mesh victims are being dismissed with the same tactics used to deny their injury claims more than 50 years ago.
The ongoing repurposing of the infamous drug thalidomide may include treatment of Crohn's disease, an incurable bowel condition.