thebaine


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Related to thebaine: Buprenorphine

the·ba·ine

 (thē′bə-ēn′, thĭ-bā′ĭn)
n.
An alkaloid, C19H21NO3, obtained from the opium poppy and used in the manufacture of oxycodone and other opioids. Also called paramorphine.

[New Latin (herba) thēbaia, (herb of) Thebes, Egyptian opium (from Latin Thēbaea, feminine of Thēbaeus, Theban, from Thēbae, Thebes, from Greek Thēbai) + -ine.]

thebaine

(ˈθiːbəˌiːn; θɪˈbeɪiːn; -aɪn)
n
(Pharmacology) a poisonous white crystalline alkaloid, found in opium but without opioid actions. Formula: C19H21NO3. Also called: paramorphine
[C19: from New Latin thebaia opium of Thebes (with reference to Egypt as a chief source of opium) + -ine2]
References in periodicals archive ?
In fact, opium poppy (P somniferum) is the predominant source of several medicinal (and potentially toxic) alkaloids, notably morphine, thebaine. papaverine, codeine, narcotine (noscopine) and narceine (although it should be noted that several other species of Papaver produce some of the same compounds).
Chris Savile, Executive Director of Commercial Operations at Intrexon, added, "As with some of our other similar projects, in thebaine, for example, microbial fermentation routes to produce cannabinoids provide advantages over traditional plant-based extraction.
Opiates are the isolated active ingredients of opium, or drugs derived from this source, eg morphine, codeine, thebaine and heroin.
Oxycodone is a semisynthetic opioid, which is synthesized from thebaine. First developed in 1917, its pharmacological action is considered to be similar to morphine and has been used clinically since [14, 15].
Buprenorphine hydrochloride is a semisynthetic highly lipophilic opioid derived from thebaine, an opium alkaloid related to morphine.
Chemical constituents: The latex is rich in alkaloids; morphine, codeine, thebaine, nacrocotine, narceine, and papaverine (Prajapati et al., 2003.
[122.] Lee S, Park Y, Han E, Choi H, Chung H, Oh SM: Thebaine in
Buprenorphine is a potent opioid derivative of the alkaloid thebaine that binds to opiate receptors and prevents the sensation of pain.
The current epidemic of prescription opioid abuse involves at least 5 different chemical entities, including morphine, codeine, thebaine, methadone, and buprenorphine, and each may require a separately developed vaccine.
1979); it showed central stimulant, hyperthermic, and spinal convulsant actions in mice, the activity profile closely resembling that of thebaine. Reticuline was identified from Argemone albiflora, A.