Comparison Of The Effects Of Etomidate, Propofol, And
Thiopental On Respiratory Resistance After Tracheal Intubation.
The protocol Chapman developed called for the (http://www.sup.org/books/title/?id=23979) use of three drugs : The first, sodium
thiopental, would anesthetize inmates and put them to sleep before the lethal drugs were administered.
A case is presented in which propofol caused a 63.1% reduction in mean seizure duration compared with preceding and subsequent treatments with
thiopental anesthesia.
The three drugs named Minoxidil, Monte Lucas and
Thiopental Sodium are used to treat blood pressure (hypertension), chronic asthma and post-anesthesia convulsion, respectively.
States have been scrambling in recent years to come up with a new formula for executions after their stockpiles expired or ran out when European manufacturers of such previously used drugs as pentobarbital and sodium
thiopental stopped selling them for use in executions.
An Oklahoma coroner suggested the three-drug protocol: sodium
thiopental, to put the inmate to sleep; pancuronium bromide, to induce paralysis; and potassium chloride, to quickly stop the heart and cause death.
After at least 3-5 minutes of preoxygenation in a 10-15[degrees] tilted position, anesthesia was induced by 4-5 mg/kg Sodium
Thiopental and 1.5-2 mg/ kg Suxamethonium.
Until recently, the 33 states with the death penalty used a virtually identical three-drug process: Sodium
thiopental was administered to put the inmate to sleep, then two other drugs stopped the heart and lungs.
Anaesthesia was induced with
Thiopental sodium intravenously and intubated.
To put a convicted killer to death, Oregon now employs a "three-drug protocol" - sodium
thiopental, pancuronium bromide, potassium chloride - that causes heart failure.
THE EUROPEAN Union, the Drug Enforcement Administration, and American prison officials are locked in an unusual battle over sodium
thiopental, a drug used for lethal injections in most state executions.
Meanwhile, in March, federal drug agents seized Georgia's supply of sodium
thiopental used in lethal injections.
