thioridazine

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Related to thioridazine: thioridazine HCl, Thioridazine hydrochloride

thi·o·rid·a·zine

(thī′ə-rĭd′ə-zēn′)

A phenothiazine drug, C₂₁H₂₆N₂S₂, that is used in the form of its hydrochloride to treat psychotic disorders.

[thio- + (pipe)rid(ine) + azine.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

thioridazine

(ˌθaɪəˈrɪdəˌziːn)

(Pharmacology) C21H26N2S2, an oral tranquillizer used to treat psychological disorders

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

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Noun

thioridazine - a tranquilizer (trade name Mellaril) used to treat schizophrenia and other psychotic disorders

Mellaril

antipsychotic, antipsychotic agent, antipsychotic drug, major tranquilizer, major tranquilliser, major tranquillizer, neuroleptic, neuroleptic agent, neuroleptic drug - tranquilizer used to treat psychotic conditions when a calming effect is desired

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Chlorpromazine (Thorazine), clozapine (Clozaril), methotrimeprazine (Nozinan), olanzapine (Zyprexa), perphenazine (Trilafon), pimozide (Orap), quetiapine (Seroquel), thioridazine (Mellaril), and trifluoperazine (Stelazine).

Q Does my anticholinergic medication increase my risk of dementia?

Antipsychotic Drugs: Clozapine, Olanzapine, Perphenazine, Quetiapine, Thioridazine, Trifluoperazine, Loxapine, Methotrimeprazine, Molindone, Pimozide

9 Drugs That Could Lead To Memory Loss And Dementia

They found that those receiving clozapine, thioridazine, and haloperidol were 2 to 3 times more likely to develop seizures than those treated with risperidone; risks associated with the rest of the FGAs were similar to that of risperidone.

Antipsychotics and seizures: What are the risks? Some agents may lower the seizure threshold, but higher-quality evidence is needed

Unfortunately, both thioridazine and clozapine have serious side effects.

Why is loxapine overlooked, underprescribed for psychosis?

Previous work in our laboratory has demonstrated that three phenothiazine derivatives, chlorpromazine, chlorprothixene, and thioridazine, have bacteriostatic activity against Neisseria species.

Microbiology

Antipsychotics with a high severity of these effects include chlorpromazine, thioridazine, clozapine, olanzapine, and haloperidol [3, 8].

Myasthenia Gravis Attack after Oral Risperidone Treatment: A Case Report

Comparing the potency over the inhibition of the K+ channels and the prolongation of the QT interval with the plasmatic therapeutic levels of the drugs, the difference between the inhibiting potency and the therapeutic dosage is greater in the case of quetiapine, olanzapine and risperidone, while thioridazine shows the lowest difference (2).

Cardiovascular effects of antipsychotics and antidepressants

Atypical antipsychotics; risperidone, olanzapine, and a typical antipsychotic, thioridazine, led to acute dystonic reactions (ADRs) in our patients.

Antipsychotic Exposures in an Emergency Department

Animal research supports the beneficial effects of sodium bicarbonate in case of thioridazine toxicity [49].

The Role of Sodium Bicarbonate in the Management of Some Toxic Ingestions

* Extreme sensitivity to antipsychotic medications used to control behavioral symptoms in other types of dementia-such as haloperidol (Haldol) and thioridazine (Mellaril)--resulting in worsening of movement disorders in people with DLB, and possibly kidney failure or even death.

Lewy body dementia: a common disease, often underdiagnosed: in this progressive disease, neurons are destroyed by toxic proteins called Lewy bodies. Dementia is the ultimate outcome

Of the commonly used antidepressants, Citalopram and Escitalopram have been found to prolong the QT interval.6 Beach et al.1 showed that Thioridazine, Ziprazidone and IV Haloperidol were the antipsychotics which had the greatest propensity for prolonging the QT interval and to be associated with Torsades de Pointes.