(NASDAQ: FENC; TSX: FRX), a specialty pharmaceutical company focused on the development of PEDMARK (a unique formulation of sodium thiosulfate
(STS)) for the prevention of platinum-induced ototoxicity in pediatric patients, today reported its business update and financial results for the second quarter ended June 30, 2019.
* Liquid Potassium Thiosulfate
mechanism (pyrite (Fe[S.sub.2]), molybdenite (Mo[S.sub.2]), and tungstenite (W[S.sub.2])), where iron(III) ions oxides metal sulfides generating thiosulfate
as intermediary and main end-product:
Other agents, including acetazolamide, probenocid and topical sodium thiosulfate
, have been reported to be beneficial with variable outcomes (8, 19, 20, 21).
Of-label treatment with sodium thiosulfate
(STS) was initiated with one intralesional application of STS (10 ml of 250 mg/ml STS solution was injected into calcifed plaques on the patient's right shin).
A large portion of sulphur is used in the production of its various derivatives such as sodium hydrosulphide, sodium hydrosulphite, sodium sulphide, sodium sulphite, sodium thiosulfate
, sulphuric acid, etc.
Our objective is to report an infrequent case of CUA treated with sodium thiosulfate
and pamidronate and showed good results.
Hexane (99.0%), cyclohexane (99.5%), ethanol (99.9%), methanol (99.9%), diethyl ether (99.0%), sodium carbonate, sodium thiosulfate
, potassium hydroxide (85.0%), potassium iodide (99.0%), sodium hydroxide (99.0%), acetic acid (99.0%), hydrochloric acid (37%), gallic acid were obtained from Merck (Germany).
, administered 6 hours after cisplatin chemotherapy, reduced the incidence of cisplatin-induced hearing loss in children with standard-risk hepatoblastoma without jeopardizing overall or event-free survival.the results presented showed that treatment was well tolerated and acute toxicity similar and expected between arms.
Technology for the production of ammonium thiosulfate
(ATS) was supplied by the American company ThioSolv.
Patch testing revealed gold sodium thiosulfate
as the cause of their allergic contact dermatitis (Dermatitis.