thiothixene


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thi·o·thix·ene

 (thī′ō-thĭk′sēn′)
n.
An antipsychotic drug, C23H29N3O2S2, used primarily in the treatment of schizophrenia.

[thio- + thi(o)x(anth)ene, compound from which thiothixene is derived (thio- + xanthene).]
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Noun1.thiothixene - a tranquilizer (trade name Navane) used to treat schizophrenia
References in periodicals archive ?
McMillin, "Simultaneous UPLC-MS/MS assay for the detection of the traditional antipsychotics haloperidol, fluphenazine, perphenazine, and thiothixene in serum and plasma," Clinica Chimica Acta, vol.
Typical antipsychotics like haloperidol, thiothixene, and flupentixol increase TST and Sleep Efficiency (SE) and reduce Sleep Latency (SL) and awakenings [5, 6].
Currently, she was taking thiothixene 20 mg three times daily (daughter had reduced it to two times daily to avoid running out) and benztropine 1mg daily.
The patient remained fever-free for the next few days and was started on Thiothixene (Navane).
Figure 2: The pharmacological agents that were tested included the following: First-generation antipsychotics: Flupenthixol decanoate Haloperidol Thiothixene Second-generation antipsychotics: Aripriprazole Olanzapine Ziprasidone Mood stabilisers: Carbamazepine Valproate semisodium Lamotrigine Topiramate Antidepressants: Amitriptyline Fluoxetine Fluvoxamine Phenelzine sulfate Mianserin Dietary supplementation: Omega-3 fatty acid However, these claims were made based on single study effects and therefore require replication.
Most (70%) were taking a drug with a moderate risk (risperidone, chlorpromazine, paliperidone, thiothixene, or trifluoperazine).
Prescribed typical antipsychotics within the study period included chlorpromazine, clopenthixol, clothiapine, droperidol, flupentixol, fluphenazine, haloperidol, levomepromazine, loxapine, methotrimeprazine, perphenazine, pipotiazine, sulpiride, thioridazine, thiothixene, and trifluoperazine.
(10,11) The drugs implicated are phenothiazines (especially chlorpromazine), thiothixene, fluphenazine, fluspirilene, loxapine and levomepromazine.
Antipsychotic Medications, Generic and Brand Names and Typical Tablet Dosage Generic Name Brand Name Tablet dosage range Atypical Risperidone Risperdal 1-3 mg Olanzapine Zyprexa 2.5-10 mg Clozapine Clozaril 25-100 mg Quetiapine Seroquel 25-200 mg Ziprasidone Geodon 20-60 mg Aripiprazole Abilify 5-15 mg High Potency Haloperidol Haldol 0.5-20 mg Typical Pimozide Orap 2 mg Fluphenazine Prolixin 2.5-10 mg Medium Potency Trifluoperazine Stelazine 1-10 mg Typical Perphenazine Trilafon 2-16 mg Thiothixene Navane 2-20 mg Loxapine Loxitane 5-50 mg Low Potency Molindone Moban 5-100 mg Typical Mesoridazine Serentil 10-100 mg Thioridazine Mellaril 10-200 mg Chlorpromazine Thorazine 10-200 mg Adapted from Wilens (1999) and Li, Pearrow, & Jimerson (2010).
In 1970 antipsychotics (haloperidol, levomepromazine, thiothixene) were recommended in Sweden as the first-line treatment of anxiety in organic brain syndromes, psychoasthenia and substance abuse.