thiothixene


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thi·o·thix·ene

 (thī′ō-thĭk′sēn′)
n.
An antipsychotic drug, C23H29N3O2S2, used primarily in the treatment of schizophrenia.

[thio- + thi(o)x(anth)ene, compound from which thiothixene is derived (thio- + xanthene).]
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Noun1.thiothixene - a tranquilizer (trade name Navane) used to treat schizophrenia
References in periodicals archive ?
The patient remained fever-free for the next few days and was started on Thiothixene (Navane).
Figure 2: The pharmacological agents that were tested included the following: First-generation antipsychotics: Flupenthixol decanoate Haloperidol Thiothixene Second-generation antipsychotics: Aripriprazole Olanzapine Ziprasidone Mood stabilisers: Carbamazepine Valproate semisodium Lamotrigine Topiramate Antidepressants: Amitriptyline Fluoxetine Fluvoxamine Phenelzine sulfate Mianserin Dietary supplementation: Omega-3 fatty acid
Most (70%) were taking a drug with a moderate risk (risperidone, chlorpromazine, paliperidone, thiothixene, or trifluoperazine).
Prescribed typical antipsychotics within the study period included chlorpromazine, clopenthixol, clothiapine, droperidol, flupentixol, fluphenazine, haloperidol, levomepromazine, loxapine, methotrimeprazine, perphenazine, pipotiazine, sulpiride, thioridazine, thiothixene, and trifluoperazine.
Lower dosage or avoid use Perphenazine Phenothiazines are contraindicated with significant hepatic impairment Thiothixene Specific guidelines not available.
10,11) The drugs implicated are phenothiazines (especially chlorpromazine), thiothixene, fluphenazine, fluspirilene, loxapine and levomepromazine.
5-10 mg Medium Potency Trifluoperazine Stelazine 1-10 mg Typical Perphenazine Trilafon 2-16 mg Thiothixene Navane 2-20 mg Loxapine Loxitane 5-50 mg Low Potency Molindone Moban 5-100 mg Typical Mesoridazine Serentil 10-100 mg Thioridazine Mellaril 10-200 mg Chlorpromazine Thorazine 10-200 mg Adapted from Wilens (1999) and Li, Pearrow, & Jimerson (2010).
Some of the drugs given this label include prochlorperazine, haloperidol, loxapine, thioridazine, molindone, thiothixene, pimozide, fluphenazine, and perphenazine.
There are several decades' worth of data from large studies supporting the reproductive safety of the typical antipsychotics such as haloperidol or thiothixene, but the reproductive safety data for the atypical antipsychotics are extremely sparse.