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Noun1.thrombasthenia - a rare autosomal recessive disease in which the platelets do not produce clots in the normal way and hemorrhage results
autosomal recessive defect, autosomal recessive disease - a disease caused by the presence of two recessive mutant genes on an autosome
References in periodicals archive ?
Glanzmann thrombasthenia (GT) is caused by an abnormality in the genes which encode glycoproteins IIb/IIIa, the glycoprotein Ilb/IIIa receptor (also called the fibrinogen receptor).
Glanzmann thrombasthenia is a severe, autosomal recessive bleeding disorder caused by a deficiency of GPIIb/IIIa, the receptor responsible for platelet aggregation.
Outside of von Willebrand in such patients, possible platelet disorders could include Glanzmann thrombasthenia (a platelet function disorder that is caused by an abnormality in the genes for glycoproteins IIb/IIIa) and platelet storage pool disorder, both of which should be diagnosed by a hematologist.
Glanzmann thrombasthenia (GT) is a rare inherited blood clotting disorder characterized by the impaired function of platelets that are essential for proper blood clotting and can lead to prolonged bleeding time.
Platelet concentrates are used in a variety of diseases, which manifests as low platelet count [10] or thrombasthenia.
Exclusion criteria: Patients with diabetes, platelet adhesion defects such as von Willebrand disease, Bernard-Soulier syndrome or platelet aggregation defects such as Glanzmann's thrombasthenia, afibrinogenemia; history of an infectious disease in the last 10 days and use of at least one of following drugs in the last two weeks: acetylsalicylic acid, clopidogrel, ticlopidine, beta lactam antibiotics, corticosteroids and non-steroidal anti-inflammatory drugs.
Characterization of platelet abnormalities, including the bleeding disorders hereditary thrombasthenia in Otterhounds, Basset Hound thrombopathia and Scott syndrome in German Shepherd Dogs.
Objective: Glanzmann~s Disease, also known as Glanzmann~s thrombasthenia (GT), and Bernard-Soulier syndrome (SBS) are autosomal recessive rare platelet disorders, characterized by severe bleeding because of the absence, reduction or dysfunction of several glycoprotein receptor complexes in platelets.
Hematology-dental integrated management in Glanzmann thrombasthenia
8] Conditions that have been associated with EC include Glanzmann's thrombasthenia, eosinophilic gastroenteritis, bronchial asthma, and coeliac disease.
Sticking pork products up the patient's nose was a treatment of last resort when conventional treatments had failed, Saraiya said, and was only used for a very specific condition known as Glanzmann thrombasthenia, a rare condition in which blood does not properly clot.