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Related to thromboplastin: Prothrombin time


A complex of protein and phospholipids that is found in tissues and platelets and facilitates blood clotting by converting prothrombin to thrombin.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) any of a group of substances that are liberated from damaged blood platelets and other tissues and convert prothrombin to thrombin. Also called: thrombokinase
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌθrɒm bəˈplæs tɪn)

a lipoprotein in the blood that converts prothrombin to thrombin.
Also called throm•bo•ki•nase (ˌθrɒm boʊˈkaɪ neɪs, -ˈkɪn eɪs)
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot
clotting factor, coagulation factor - any of the factors in the blood whose actions are essential for blood coagulation
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Reported FIX activity was measured using an activated partial thromboplastin time assay performed at a central laboratory.
The most common adverse reactions reported in patients treated with ALUNBRIG at the recommended 180 mg dosing regimen were increased aspartate aminotransferase, hyperglycemia, hyperinsulinemia, anemia, increased creatine phosphokinase, nausea, increased lipase, decreased lymphocyte count, increased alanine aminotransferase, diarrhea, increased amylase, fatigue, cough, headache, increased alkaline phosphatase, hypophosphatemia, increased abnormal activated partial thromboplastin time, rash, vomiting, dyspnea, hypertension, decreased blood cell count, myalgia, and peripheral neuropathy.
[6] This pathway can be analyzed by measuring activated partial thromboplastin time (aPTT) [5] thereby measuring the functional activity of Factors IX, X, XI, and XII.
(2) The 3.8% sodium citrated plasma appears to alter the International Sensitivity Index (ISI) of some thromboplastin times (3-5) but is still the preferred material for special platelet function tests.
However, her laboratory tests deserve some comments: there was a strong presence of LA according to the dilute Russell's viper venom time (DRWT), but the activated partial thromboplastin time (APTT) was within the reference interval.
Initial coagulation parameters were recorded and included initial international normalized ratio, postreversal international normalized ratio, initial activated partial thromboplastin time, postreversal activated partial thromboplastin time, initial prothrombin time, and postreversal prothrombin time.
Suspecting neonatal Purpura Fulminans, laboratory investigations including complete blood count (CBC), Prothrombin time (PT), Activated Partial Thromboplastin Time (APTT), Protein C, and Protein S were sent which showed following results:
The partial thromboplastin time has been the gold standard for monitoring.
Prothrombin time and activated partial thromboplastin time, albumin levels and alpha-1 antitrypsin value checked for liver failure were normal.
The reason cuts that result from blunt trauma don't bleed as much as wounds from sharp cuts is because the trauma stimulates the release of Thromboplastin. This is a plasma protein that rapidly aids in blood coagulation.
Activated partial thromboplastin time (aPTT) was prolonged at 47.7 seconds.

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